实用癌症杂志
實用癌癥雜誌
실용암증잡지
The Practical Journal of Cancer
2015年
8期
1218-1220
,共3页
腹腔灌洗%胃癌%腹腔转移
腹腔灌洗%胃癌%腹腔轉移
복강관세%위암%복강전이
Peritoneal lavage%Gastric cancer%Peritoneal metastasis
目的 探讨腹腔灌洗对胃癌患者发生腹腔转移的预防效果及预后分析. 方法 回顾性分析70例胃癌患者的临床病理资料. 37例接受了根治性切除且行腹腔灌洗,33例接受了根治性切除非腹腔灌洗. 根据临床病理特征,对无病生存期(DFS)、总生存期(OS)和复发模式进行了分析. 结果 患者根治性切除后的中位DFS和OS分别为10(1~33)个月和15(2~45)个月,中位随访时间为16.1(3 ~45)个月. 腹腔灌洗患者的1-,2-,3-和4 年生存率分别为63.8%,58.6%,25.4%和10.7%. 非腹腔灌洗患者均有复发,30例(90.9%)有腹腔扩散. 33例患者的1-,2-,3-和4年生存率分别为43.2%,45.9%,5.4%和0%. 多元线性回归分析显示,Borrmann分型Ⅳ是一个独立的预测因子,预后较差. 结论 腹腔灌注灌洗疗法对胃癌细胞腹腔转移有一定的预防作用,安全可靠,副作用小,在临床中有一定的指导意义.
目的 探討腹腔灌洗對胃癌患者髮生腹腔轉移的預防效果及預後分析. 方法 迴顧性分析70例胃癌患者的臨床病理資料. 37例接受瞭根治性切除且行腹腔灌洗,33例接受瞭根治性切除非腹腔灌洗. 根據臨床病理特徵,對無病生存期(DFS)、總生存期(OS)和複髮模式進行瞭分析. 結果 患者根治性切除後的中位DFS和OS分彆為10(1~33)箇月和15(2~45)箇月,中位隨訪時間為16.1(3 ~45)箇月. 腹腔灌洗患者的1-,2-,3-和4 年生存率分彆為63.8%,58.6%,25.4%和10.7%. 非腹腔灌洗患者均有複髮,30例(90.9%)有腹腔擴散. 33例患者的1-,2-,3-和4年生存率分彆為43.2%,45.9%,5.4%和0%. 多元線性迴歸分析顯示,Borrmann分型Ⅳ是一箇獨立的預測因子,預後較差. 結論 腹腔灌註灌洗療法對胃癌細胞腹腔轉移有一定的預防作用,安全可靠,副作用小,在臨床中有一定的指導意義.
목적 탐토복강관세대위암환자발생복강전이적예방효과급예후분석. 방법 회고성분석70례위암환자적림상병리자료. 37례접수료근치성절제차행복강관세,33례접수료근치성절제비복강관세. 근거림상병리특정,대무병생존기(DFS)、총생존기(OS)화복발모식진행료분석. 결과 환자근치성절제후적중위DFS화OS분별위10(1~33)개월화15(2~45)개월,중위수방시간위16.1(3 ~45)개월. 복강관세환자적1-,2-,3-화4 년생존솔분별위63.8%,58.6%,25.4%화10.7%. 비복강관세환자균유복발,30례(90.9%)유복강확산. 33례환자적1-,2-,3-화4년생존솔분별위43.2%,45.9%,5.4%화0%. 다원선성회귀분석현시,Borrmann분형Ⅳ시일개독립적예측인자,예후교차. 결론 복강관주관세요법대위암세포복강전이유일정적예방작용,안전가고,부작용소,재림상중유일정적지도의의.
Objective To investigate the preventive effect of peritoneal lavage in gastric cancer patients with peritoneal metastasisand prognosis.Methods A retrospective analysis of clinicopathological data of 70 patients with gastric cancer were conducted.37 cases underwent radical resection and intraperitoneal lavage,33 cases underwent radical resection of non-peritoneal lavage.According to the clinicopathological features,disease-free survival ( DFS) and overall survival ( OS) ,and recurrence pat-terns were analyzed.Results Patients after radical resection,the median DFS and OS were 10 months ( range 1~33 months) and 15 months (range 2~45 months),with a median follow-up time of 16.1 months (range 3~45 months).1-,2-,3-and 4-year survival rates of patients with peritoneal lavage were,respectively,63.8%,58.6%,25.4% and 10.7%.Non-peritoneal lavage patients all had relapsed,30 cases (90.9%) had abdominal spread.1-,2-,3-and 4-year survival rates of 33 patients were 43.2%,45.9%,5.4%and 0%.Multiple linear regression analysis showed that Borrmann typeⅣis an independent predictor of poor prognosis.Conclusion Peritoneal lavage for metastasis of gastric cancer cells have a preventive effect,and it is safe with less side effects,there is a certain significance in practice.
