中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
Chinese Journal of Practical Ophthalmology
2015年
7期
789-794
,共6页
郑策%谢晓玲%陈文霞%张铭志
鄭策%謝曉玲%陳文霞%張銘誌
정책%사효령%진문하%장명지
可重复性%AS-OCT%虹膜厚度%虹膜面积%虹膜曲度
可重複性%AS-OCT%虹膜厚度%虹膜麵積%虹膜麯度
가중복성%AS-OCT%홍막후도%홍막면적%홍막곡도
Reproducibility%AS-OCT%Iris thickness%Iris area%Iris curvature
目的 评估使用眼前节光学相干断层成像术(AS-OCT)定量测量虹膜参数的可重复性.方法 横断面研究.对2013年1月至2015年1月在汕头国际眼科中心共纳入受试者105名,平均年龄48.5岁(24～67岁).分为房角开放(50名受试者)和房角关闭(55名受试者)两组.采用AS-OCT的眼前节单线扫描模式,使用自编程图像处理软件定量测量AS-OCT影像的虹膜参数,包括虹膜厚度,虹膜体积和虹膜曲度.先由一名检查者在不同时间对受试者进行2次检查.再由第二位独立检查者对受试者进行第三次检查.测量不分先后顺序,测量结果双盲.运用组内相关系数(ICC),变异系数(COV)来评估测量者间和测量者内的可重复性.结果 房角开放眼的虹膜厚度,虹膜面积和虹膜曲度的平均值±标准差分别为(0.40±0.05) mm,(1.67±0.24) mm2和(0.18±0.12) mm;房角关闭眼的虹膜参数分别为(0.42±0.04) mm,(1.62±0.25) mrn2和(0.25±0.11)mm.在房角开放眼组,测量者内和测量者间得出的虹膜厚度,虹膜面积,虹膜曲度的ICC值为0.865～0.982.在房角关闭眼组的ICC值为0.875～0.948.结论 使用AS-OCT定量测量房角开放和房角关闭眼的虹膜参数均可获得高度可重复性.
目的 評估使用眼前節光學相榦斷層成像術(AS-OCT)定量測量虹膜參數的可重複性.方法 橫斷麵研究.對2013年1月至2015年1月在汕頭國際眼科中心共納入受試者105名,平均年齡48.5歲(24～67歲).分為房角開放(50名受試者)和房角關閉(55名受試者)兩組.採用AS-OCT的眼前節單線掃描模式,使用自編程圖像處理軟件定量測量AS-OCT影像的虹膜參數,包括虹膜厚度,虹膜體積和虹膜麯度.先由一名檢查者在不同時間對受試者進行2次檢查.再由第二位獨立檢查者對受試者進行第三次檢查.測量不分先後順序,測量結果雙盲.運用組內相關繫數(ICC),變異繫數(COV)來評估測量者間和測量者內的可重複性.結果 房角開放眼的虹膜厚度,虹膜麵積和虹膜麯度的平均值±標準差分彆為(0.40±0.05) mm,(1.67±0.24) mm2和(0.18±0.12) mm;房角關閉眼的虹膜參數分彆為(0.42±0.04) mm,(1.62±0.25) mrn2和(0.25±0.11)mm.在房角開放眼組,測量者內和測量者間得齣的虹膜厚度,虹膜麵積,虹膜麯度的ICC值為0.865～0.982.在房角關閉眼組的ICC值為0.875～0.948.結論 使用AS-OCT定量測量房角開放和房角關閉眼的虹膜參數均可穫得高度可重複性.
목적 평고사용안전절광학상간단층성상술(AS-OCT)정량측량홍막삼수적가중복성.방법 횡단면연구.대2013년1월지2015년1월재산두국제안과중심공납입수시자105명,평균년령48.5세(24～67세).분위방각개방(50명수시자)화방각관폐(55명수시자)량조.채용AS-OCT적안전절단선소묘모식,사용자편정도상처리연건정량측량AS-OCT영상적홍막삼수,포괄홍막후도,홍막체적화홍막곡도.선유일명검사자재불동시간대수시자진행2차검사.재유제이위독립검사자대수시자진행제삼차검사.측량불분선후순서,측량결과쌍맹.운용조내상관계수(ICC),변이계수(COV)래평고측량자간화측량자내적가중복성.결과 방각개방안적홍막후도,홍막면적화홍막곡도적평균치±표준차분별위(0.40±0.05) mm,(1.67±0.24) mm2화(0.18±0.12) mm;방각관폐안적홍막삼수분별위(0.42±0.04) mm,(1.62±0.25) mrn2화(0.25±0.11)mm.재방각개방안조,측량자내화측량자간득출적홍막후도,홍막면적,홍막곡도적ICC치위0.865～0.982.재방각관폐안조적ICC치위0.875～0.948.결론 사용AS-OCT정량측량방각개방화방각관폐안적홍막삼수균가획득고도가중복성.
Objective To determine the repeatability and reproducibility of anterior segment optical coherence tomography (AS-OCT) on the measurement of iris parameters.Methods In this cross-sectional study,105 consecutive subjects,mean age was 48.5 years (range:24-67),(50 normal open angle subjects and 55 angle-closure subjects) were recruited.One eye from each subject was randomly selected for imaging by AS-OCT using anterior segment single protocol.For intraobserver and interobserver reproducibility,a single observer acquired two sets of images followed by a third set of images acquired by a second observer.AS-OCT images were measured using custom software to determine iris parameters,including iris thickness,iris area and iris curvature.The intraclass correlation coefficient (ICC),limits of agreement (LOA;mean of differences± 1.96SD of differences),and coefficient of variation (CV) were calculated as items of intraobserver and interobserver reproducibility.Results The mean and standard deviation of iris thickness,iris area and iris curvature,in open angle group,were 0.40±0.05mm,1.67±0.24 mm2 and 0.18±0.12 mm,respectively;and in angle-closure group,were 0.42±0.04 mm,1.62±0.25 mm2 and 0.25±0.11 mm,respectively.In open angle group,ICC of intraobserver and interobserver measurement was from 0.865 to 0.982.In angle-closure group,the range of ICC was from 0.875 to 0.948.Conclusions The reproducibility of iris parameters measurements with the AS-OCT is good in both open angle and angle closure eyes.
