东南大学学报（医学版）
東南大學學報（醫學版）
동남대학학보（의학판）
Journal of Southeast University (Medical Science Edition)
2015年
5期
745-748
,共4页
胡凯%HAMRAH Pedram
鬍凱%HAMRAH Pedram
호개%HAMRAH Pedram
角膜共聚焦显微镜%干眼%治疗方案调整
角膜共聚焦顯微鏡%榦眼%治療方案調整
각막공취초현미경%간안%치료방안조정
corneal confocal microscopy%dry eye disease%treating protocol modification
目的：评价角膜共聚焦显微镜检查在干眼随访诊治中的作用。方法：选取干眼新发病例150例（300眼），随机分为A、B两组，随访治疗半年。 A组患者根据随访角膜共聚焦显微镜检查结果调整治疗方案，B组根据常规干眼检查结果调整治疗方案，两组所用具体治疗药物及方法相同。结果：A组患者总的好转率为63％，明显高于B组的35％；并且经治疗后，A组患者的平均泪液分泌量（SⅠt）及泪膜破裂时间（BUT）明显好于B组。结论：根据角膜共聚焦显微镜检查结果调整干眼治疗方案效果明显好于传统随访治疗方案。
目的：評價角膜共聚焦顯微鏡檢查在榦眼隨訪診治中的作用。方法：選取榦眼新髮病例150例（300眼），隨機分為A、B兩組，隨訪治療半年。 A組患者根據隨訪角膜共聚焦顯微鏡檢查結果調整治療方案，B組根據常規榦眼檢查結果調整治療方案，兩組所用具體治療藥物及方法相同。結果：A組患者總的好轉率為63％，明顯高于B組的35％；併且經治療後，A組患者的平均淚液分泌量（SⅠt）及淚膜破裂時間（BUT）明顯好于B組。結論：根據角膜共聚焦顯微鏡檢查結果調整榦眼治療方案效果明顯好于傳統隨訪治療方案。
목적：평개각막공취초현미경검사재간안수방진치중적작용。방법：선취간안신발병례150례（300안），수궤분위A、B량조，수방치료반년。 A조환자근거수방각막공취초현미경검사결과조정치료방안，B조근거상규간안검사결과조정치료방안，량조소용구체치료약물급방법상동。결과：A조환자총적호전솔위63％，명현고우B조적35％；병차경치료후，A조환자적평균루액분비량（SⅠt）급루막파렬시간（BUT）명현호우B조。결론：근거각막공취초현미경검사결과조정간안치료방안효과명현호우전통수방치료방안。
Objective: To evaluate the role of confocal microscopy corneal examination in determining the treatments during the follow-up period of dry eye patients.Methods: 150 dry eye patients ( 300 eyes ) were diagnosed and treated, and grouped A and B, followed up for half a year.The treatments of patients in group A were modified according to the changes of confocal microscopy corneal examination, whereas those of group B were done based on the usual dry eye clinical tests, except for which, the drugs and treatments were consistent between group A and B.Results: The total improvement rate of patients in group A were 63%, which was significantly higher than that of group B ( 35%); the SIt and BUT levels of patients in group A after treatments were both significantly better than those of group B.Conclusion: The therapeutic effect of dry eye patients modified aaccording to the changes of confocal microscopy corneal examination is significantly better than that modified according to the usual follow-up dry eye tests.
