中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
Chinese Journal of Practical Ophthalmology
2015年
7期
720-723
,共4页
卫承华%戴巧云%晋毓信%许玉娟%陆维真%王玺%韦超兵%赵海峰
衛承華%戴巧雲%晉毓信%許玉娟%陸維真%王璽%韋超兵%趙海峰
위승화%대교운%진육신%허옥연%륙유진%왕새%위초병%조해봉
屈光角膜切削术%治疗性角膜切屑术%近视
屈光角膜切削術%治療性角膜切屑術%近視
굴광각막절삭술%치료성각막절설술%근시
Phototherapeutic keratectomy%Photorefractive keratectomy%Myopia
目的 比较分析Nidek EC-5000治疗性角膜切削术(phototherapeutic keratectomy,PTK)联合屈光性角膜切削术(photorefractive keratectomy,PRK)与经典PRK手术临床治疗效果.方法 前瞻性临床研究.对2012年7月至2013年6月在弋矶山医院眼科就诊的30例近视患者,应用随机数字法随机分成2组,15例30只眼采用两步法PTK-PRK手术(组1),15例30只眼行经典PRK手术(组2).术后评估患者痛疼程度、角膜上皮愈合时间、屈光度、角膜上皮雾状混浊(HAZE)反应程度和视力.结果 角膜上皮愈合时间组l为(2.37±0.61)d,组2为(2.90±0.66)d,差异有统计学意义(t =-3.23,P＜0.05);疼痛程度评分组1为(3.30±1.09)分,组2为(3.56±0.97)分,差异无统计学意义(Z =-0.96,P=0.34);上皮愈合后早期裸眼视力组1为(0.30±0.10) logMAR,组2为(0.22±0.12) logMAR,差异有统计学意义(t=2.55,P=0.013);术后6个月组1的裸眼视力(0.003±0.018)logMAR,组2的裸眼视力(0.007±0.025) logMAR,差异无统计学意义(t=-0.58,P=0.56);组1和组2术后HAZE反应差异无统计学意义(Z =-0.32,P=0.75);术后6个月等效球镜度组1(+0.33±0.21)D,组2(+0.13±0.19)D,差异有统计学意义(t=3.91,P＜0.05).结论 PTK-PRK与经典PRK术式相比有相同的安全性和有效性,术后能较快修复角膜上皮,屈光度有远视偏移.
目的 比較分析Nidek EC-5000治療性角膜切削術(phototherapeutic keratectomy,PTK)聯閤屈光性角膜切削術(photorefractive keratectomy,PRK)與經典PRK手術臨床治療效果.方法 前瞻性臨床研究.對2012年7月至2013年6月在弋磯山醫院眼科就診的30例近視患者,應用隨機數字法隨機分成2組,15例30隻眼採用兩步法PTK-PRK手術(組1),15例30隻眼行經典PRK手術(組2).術後評估患者痛疼程度、角膜上皮愈閤時間、屈光度、角膜上皮霧狀混濁(HAZE)反應程度和視力.結果 角膜上皮愈閤時間組l為(2.37±0.61)d,組2為(2.90±0.66)d,差異有統計學意義(t =-3.23,P＜0.05);疼痛程度評分組1為(3.30±1.09)分,組2為(3.56±0.97)分,差異無統計學意義(Z =-0.96,P=0.34);上皮愈閤後早期裸眼視力組1為(0.30±0.10) logMAR,組2為(0.22±0.12) logMAR,差異有統計學意義(t=2.55,P=0.013);術後6箇月組1的裸眼視力(0.003±0.018)logMAR,組2的裸眼視力(0.007±0.025) logMAR,差異無統計學意義(t=-0.58,P=0.56);組1和組2術後HAZE反應差異無統計學意義(Z =-0.32,P=0.75);術後6箇月等效毬鏡度組1(+0.33±0.21)D,組2(+0.13±0.19)D,差異有統計學意義(t=3.91,P＜0.05).結論 PTK-PRK與經典PRK術式相比有相同的安全性和有效性,術後能較快脩複角膜上皮,屈光度有遠視偏移.
목적 비교분석Nidek EC-5000치료성각막절삭술(phototherapeutic keratectomy,PTK)연합굴광성각막절삭술(photorefractive keratectomy,PRK)여경전PRK수술림상치료효과.방법 전첨성림상연구.대2012년7월지2013년6월재익기산의원안과취진적30례근시환자,응용수궤수자법수궤분성2조,15례30지안채용량보법PTK-PRK수술(조1),15례30지안행경전PRK수술(조2).술후평고환자통동정도、각막상피유합시간、굴광도、각막상피무상혼탁(HAZE)반응정도화시력.결과 각막상피유합시간조l위(2.37±0.61)d,조2위(2.90±0.66)d,차이유통계학의의(t =-3.23,P＜0.05);동통정도평분조1위(3.30±1.09)분,조2위(3.56±0.97)분,차이무통계학의의(Z =-0.96,P=0.34);상피유합후조기라안시력조1위(0.30±0.10) logMAR,조2위(0.22±0.12) logMAR,차이유통계학의의(t=2.55,P=0.013);술후6개월조1적라안시력(0.003±0.018)logMAR,조2적라안시력(0.007±0.025) logMAR,차이무통계학의의(t=-0.58,P=0.56);조1화조2술후HAZE반응차이무통계학의의(Z =-0.32,P=0.75);술후6개월등효구경도조1(+0.33±0.21)D,조2(+0.13±0.19)D,차이유통계학의의(t=3.91,P＜0.05).결론 PTK-PRK여경전PRK술식상비유상동적안전성화유효성,술후능교쾌수복각막상피,굴광도유원시편이.
Objective To evaluate clinical results after transepithelial photorefractive keratectomy (PTK-PRK) performed with the NIDEK EC5000 excimer laser machine or conventional photorefractive keratectomy (PRK).Methods In this prospective study,60 eyes from 30 patients with myopia underwent transepithelial PRK perform PTK followed by PRK (30 eyes,group one) or conventional PRK (30 eyes,group two).The epithelium was removed with the excimer laser in group one.Epithelial healing was evaluated every 24 hours until complete reepithelialization.Postoperative pain was evaluated according to the five scales.All outcomes were reported for 6 months postoperatively.Results Mean reepithelialization took (2.37±0.61) days in group one and (2.90±0.66) days in group two (t =-3.23,P ＜0.05),mean pain score was (3.30±1.09) in group one and (3.56±0.97) in group two (Z =-0.96,P＞0.05).The comea reepithelialing uncorrected distant visual acuity was (0.30±0.10) logMAR in group one and (0.22±0.12) logMAR in group two (t =2.55,P =0.013).Six months postoperation distant uncorrected visual acuity was 1.0 for 29 eyes,0.8 for 1 eye in group one and 1.0 for 28 eyes,0.8 for 2 eyes in group two (t =-0.58,P =0.56).Six months postoperation of manifest refraction was (+0.33±0.21) D in group one and (+0.13±0.19) D in group two (t=3.91,P ＜0.05).The HAZE scale scores were tested between 2 groups (Z =-0.32,P ＞0.05).Conclusions Preliminary study show PTK-PRK is as safe and effective as conventional PRK.The PTK-PRK performs more rapid reepithelialization and has hyperopia optic result.
