CAJ | 학술논문

目的：分析自拟心衰方对气虚血瘀型慢性心力衰竭患者的临床疗效。方法160例门诊及住院慢性心力衰竭患者按随机数字表分为两组，每组80例。对照组给予心衰基础西药治疗，治疗组在此基础上给予自拟心衰方治疗，每周复查1次，病情变化时随时就诊。结果两组病例治疗后中医临床疗效、总有效率比较差异有统计学意义（P ﹤0.05）。两组病例治疗后 LVEd 明显减少（P ﹤0.05），IVS、LVPW 及 EF 显著增加（P ﹤0.05），且治疗组优于对照组（P ﹤0.05）。两组病例再住院率比较差异有统计学意义（P ﹤0.05），两组病例死亡率比较差异无统计学意义。结论自拟心衰方联合常规西药治疗气虚血瘀型慢性心力衰竭，能明显改善临床症状、中医症候积分，且能明显降低再住院率。
목적：분석자의심쇠방대기허혈어형만성심력쇠갈환자적림상료효。방법160례문진급주원만성심력쇠갈환자안수궤수자표분위량조，매조80례。대조조급여심쇠기출서약치료，치료조재차기출상급여자의심쇠방치료，매주복사1차，병정변화시수시취진。결과량조병례치료후중의림상료효、총유효솔비교차이유통계학의의（P ﹤0.05）。량조병례치료후 LVEd 명현감소（P ﹤0.05），IVS、LVPW 급 EF 현저증가（P ﹤0.05），차치료조우우대조조（P ﹤0.05）。량조병례재주원솔비교차이유통계학의의（P ﹤0.05），량조병례사망솔비교차이무통계학의의。결론자의심쇠방연합상규서약치료기허혈어형만성심력쇠갈，능명현개선림상증상、중의증후적분，차능명현강저재주원솔。
Objective To analyze the clinical efficacy on chronic heart failure of qi deficiency and blood stagnation pattern treated with self - prepared xinshuai formula. Methods One hundred and sixty out-patients and inpatients of chronic heart failure were randomized into two groups,80 cases in each one. In the control group,the basic western medication was administered. In the treatment group,on the basic treatment as the control group,the self - prepared xinshuai formula was applied. The patient was re - examined once ev-ery week and treated accordingly. Results After treatment,the clinical efficacy and total effectively rate were different between the two groups(P ﹤ 0. 05). After treatment,LVEd was reduced apparently( P ﹤ 0. 05), IVS,LVPW and EF were increased significantly(P ﹤ 0. 05)in the two groups. The results in the treatment group were better than those in the control group(P ﹤ 0. 05). The re - admission rate was different signifi-cantly between the two groups(P ﹤ 0. 05). The death rate was not significantly different between the two groups. Conclusion The combined medication of self - prepared xinshuai formula and conventional western medicine apparently relieves clinical symptoms and TCM symptom score and reduces re - admission rate in the patients of chronic heart failure differentiated as qi deficiency and blood stagnation.