CAJ | 학술논문

目的：评价超声弹性成像技术用于诊断前列腺癌的有效性与安全性。方法选取疑似前列腺癌患者83例，分别对其应用经直肠超声弹性成像（TRTE）和经直肠超声成像（TRUS）技术进行诊断。以患者的手术病理为诊断依据，比较两种方法的诊断效果。结果83例患者共有结节102个，其中有44例患者的的病理结果为良性，共49个结节；39例为恶性，共53个结节。102个结节中有47个为内腺结节，占46．08％；55个为外腺结节，占53．92％。共发现癌灶54个，TRTE 检出36个，检出率为66．67％，TRUS 仅检出24个，检出率为44．44％。TRTE 诊断的敏感性、特异性以及准确性分别为66．67％、68．65％与67．64％，均高于相应TRUS 诊断的44．44％、64．58％与53．92％，各项比较差异有统计学意义（χ2＝10．710，P ＜0．05；χ2＝3．879， P ＜0．05；χ2＝4．084，P ＜0．05）。所选患者的良、恶性前列腺结节病理检查结果与 TRUE、TRUS 检查结果差异均无统计学意义（均 P ＞0．05）。结论将超声弹性成像技术用于诊断前列腺癌具有很好的敏感性、特异性以及准确性，可提高临床诊断效果，值得临床推广应用。
목적：평개초성탄성성상기술용우진단전렬선암적유효성여안전성。방법선취의사전렬선암환자83례，분별대기응용경직장초성탄성성상（TRTE）화경직장초성성상（TRUS）기술진행진단。이환자적수술병리위진단의거，비교량충방법적진단효과。결과83례환자공유결절102개，기중유44례환자적적병리결과위량성，공49개결절；39례위악성，공53개결절。102개결절중유47개위내선결절，점46．08％；55개위외선결절，점53．92％。공발현암조54개，TRTE 검출36개，검출솔위66．67％，TRUS 부검출24개，검출솔위44．44％。TRTE 진단적민감성、특이성이급준학성분별위66．67％、68．65％여67．64％，균고우상응TRUS 진단적44．44％、64．58％여53．92％，각항비교차이유통계학의의（χ2＝10．710，P ＜0．05；χ2＝3．879， P ＜0．05；χ2＝4．084，P ＜0．05）。소선환자적량、악성전렬선결절병리검사결과여 TRUE、TRUS 검사결과차이균무통계학의의（균 P ＞0．05）。결론장초성탄성성상기술용우진단전렬선암구유흔호적민감성、특이성이급준학성，가제고림상진단효과，치득림상추엄응용。
Objective To evaluate the efficacy and safety of ultrasound elastography in the diagnosis of pros-tate cancer.Methods 83 patients with prostate cancer were selected and diagnosed by transrectal ultrasound elastog-raphy (TRTE)and transrectal ultrasound(TRUS).The surgical pathology of the patients was used as diagnosis basis, and the efficacy of the two methods was evaluated.Results There were 102 nodules of all the 83 patients,44 patients'surgical pathology were benign,a total of 49 nodules,39 cases were vicious,a total of 53 nodules.47 nodules were gland nodules,accounting for 46.08% and 55 nodules were outer gland nodules,accounting for 53.92% of all the 102 nodules.There were 54 focis,the TRTE detected 36 focis,the detection rate was 66.67%,and TRUS detected 24 focis,the detection rate was 44.44%.The sensitivity,specificity and accuracy rates of TRTE were 66.67%, 68.65% and 67.64%,which were higher than 44.44%,64.58% and 53.92% of TRUS,and the differences were statistically significant (χ2 =10.710,P <0.05;χ2 =3.879,P <0.05;χ2 =4.084,P <0.05).The differences of pathological findings and TRTE,TRUS findings of the benign and malignant prostate nodules were not statistically significant (P >0.05 ).Conclusion It has higher diagnostic sensitivity,specificity and diagnostic accuracy for ultrasound elastography in the diagnosis of prostate cancer,which can improve the clinical diagnostic performance and worthy of clinical application.