吉林中医药
吉林中醫藥
길림중의약
Jilin Journal of Traditional Chinese Medicine
2015年
9期
889-892
,共4页
多囊卵巢综合征%中医证型%胰岛素水平%胰岛素抵抗%脾虚痰湿%肾虚%肝郁气滞
多囊卵巢綜閤徵%中醫證型%胰島素水平%胰島素牴抗%脾虛痰濕%腎虛%肝鬱氣滯
다낭란소종합정%중의증형%이도소수평%이도소저항%비허담습%신허%간욱기체
polycystic ovary syndrome%TCM syndrome%FINS%insulin resistance%spleen deficiency and wet phlegm%kidney deficiency%liver and qi stagnation
目的：探讨多囊卵巢综合征（PCOS）不同中医证型与胰岛素抵抗之间的关系。方法234例PCOS患者，测量身高和体质量，计算体质量指数（BMI ），诊断糖耐量异常，生化检测血清中胰岛素水平（FINS ）、胰岛素生长因子结合球蛋白－Ⅰ水平（IGFBP－Ⅰ）、空腹葡萄糖水平（FPG ），计算胰岛素抵抗指数（HOMA－IRH ）。结果肾虚组和肝郁气滞组与脾虚痰湿组比较差异具有统计学意义（ P＜0.05），肾虚组、肝郁气滞组和脾虚组的BMI、FINS、FPG、IGFBP－Ⅰ、HOMA－IRH均显著高于正常对照组（ P＜0.05），肾虚组和肝郁气滞组与脾虚组比较有统计学意义（ P＜0.05）。肾虚组和肝郁气滞组的糖耐量异常与HOMA－IRH异常所占比例与脾虚组比较有统计学意义。结论 PCOS主要为脾虚痰湿证型，不同中医证型与胰岛素抵抗有密切联系，脾虚证型与胰岛素抵抗关系最为紧密。
目的：探討多囊卵巢綜閤徵（PCOS）不同中醫證型與胰島素牴抗之間的關繫。方法234例PCOS患者，測量身高和體質量，計算體質量指數（BMI ），診斷糖耐量異常，生化檢測血清中胰島素水平（FINS ）、胰島素生長因子結閤毬蛋白－Ⅰ水平（IGFBP－Ⅰ）、空腹葡萄糖水平（FPG ），計算胰島素牴抗指數（HOMA－IRH ）。結果腎虛組和肝鬱氣滯組與脾虛痰濕組比較差異具有統計學意義（ P＜0.05），腎虛組、肝鬱氣滯組和脾虛組的BMI、FINS、FPG、IGFBP－Ⅰ、HOMA－IRH均顯著高于正常對照組（ P＜0.05），腎虛組和肝鬱氣滯組與脾虛組比較有統計學意義（ P＜0.05）。腎虛組和肝鬱氣滯組的糖耐量異常與HOMA－IRH異常所佔比例與脾虛組比較有統計學意義。結論 PCOS主要為脾虛痰濕證型，不同中醫證型與胰島素牴抗有密切聯繫，脾虛證型與胰島素牴抗關繫最為緊密。
목적：탐토다낭란소종합정（PCOS）불동중의증형여이도소저항지간적관계。방법234례PCOS환자，측량신고화체질량，계산체질량지수（BMI ），진단당내량이상，생화검측혈청중이도소수평（FINS ）、이도소생장인자결합구단백－Ⅰ수평（IGFBP－Ⅰ）、공복포도당수평（FPG ），계산이도소저항지수（HOMA－IRH ）。결과신허조화간욱기체조여비허담습조비교차이구유통계학의의（ P＜0.05），신허조、간욱기체조화비허조적BMI、FINS、FPG、IGFBP－Ⅰ、HOMA－IRH균현저고우정상대조조（ P＜0.05），신허조화간욱기체조여비허조비교유통계학의의（ P＜0.05）。신허조화간욱기체조적당내량이상여HOMA－IRH이상소점비례여비허조비교유통계학의의。결론 PCOS주요위비허담습증형，불동중의증형여이도소저항유밀절련계，비허증형여이도소저항관계최위긴밀。
Objective To investigate the relationship between the different type of TCM syndrome and insulin resistance in polycystic ovary syndrome (PCOS ) .Methods The 234 cases of PCOS patients ,measuring height and weight to calculate body mass index (BMI) ,the diagnosis of impaired glucose tolerance ,serum insulin levels in biochemistry (FINS) ,insulin-like growth factor-Ⅰ binding globulin levels (IGFBP-Ⅰ) ,fasting glucose levels (FPG ) ,insulin resistance index (HOMA-IRH ) .Results The results of kidney group and the group with spleen qi stagnation phlegm group has statistical significance ( P<0 .05 ) ,kidney group ,BMI group and spleen qi stagnation group ,FINS ,FPG ,IGFBP-Ⅰ ,HOMA-IRH were significantly higher than the control group ( P<0 .05 ) ,there was a statistical significance ( P<0 .05 ) groups ,and kidney and spleen qi stagnation group .Kidney group tolerance and abnormal liver and qi stagnation group had significant difference compared with the proportion of abnormal HOMA-IRH group and spleen .Conclusion PCOS symptoms mainly spleen phlegm type ,a dif-ferent type of traditional Chinese medicine syndrome and insulin resistance are closely linked closely ,spleen intrinsic rela-tionship is most closely associated with insulin resistance .
