CAJ | 학술논문

目的：探讨真菌、幽门螺杆菌感染在胃癌检出中的病理情况。方法回顾性分析2010年1月至2013年1月淮南朝阳医院诊治的胃癌患者（胃癌组）和慢性萎缩性胃炎患者（慢性萎缩性胃炎组）的临床资料，各45例，均采用常规石蜡切片、苏木精-伊红染色、特殊染色，免疫组织化学染色和聚合酶链反应扩增方法对标本进行研究，观察真菌和幽门螺杆菌检出情况。结果胃癌组中，真菌检出26例，占57.8％，幽门螺杆菌检出34例，占75.6％；慢性萎缩性胃炎组中，真菌检出0例，幽门螺杆菌检出12例，占26.7％。两组幽门螺杆菌检出率和真菌检出率比较，差异均有统计学意义（ P＜0.05）。结论真菌、幽门螺杆菌感染均是诱发胃癌的致病菌。
목적：탐토진균、유문라간균감염재위암검출중적병리정황。방법회고성분석2010년1월지2013년1월회남조양의원진치적위암환자（위암조）화만성위축성위염환자（만성위축성위염조）적림상자료，각45례，균채용상규석사절편、소목정-이홍염색、특수염색，면역조직화학염색화취합매련반응확증방법대표본진행연구，관찰진균화유문라간균검출정황。결과위암조중，진균검출26례，점57.8％，유문라간균검출34례，점75.6％；만성위축성위염조중，진균검출0례，유문라간균검출12례，점26.7％。량조유문라간균검출솔화진균검출솔비교，차이균유통계학의의（ P＜0.05）。결론진균、유문라간균감염균시유발위암적치병균。
Objective To investigate the pathology of detection of the mould ,Helicobacter pylori infec-tion in gastric cancer.Methods Retrospective analysis of clinical data of 45 cases of gastric cancer and 45 cases of chronic atrophic gastritis from Huainan Chaoyang Hospital during Jan.2010 and Jan.2013 was done, the specimen were all studied by paraffin sections,hematoxylin eosin staining,special staining,immunohisto-chemistry and polymerase chain reaction method,to observe the detection situation of the mould and Helico-bacter pylori.Resutts In the gastric cancer group,the number of detected mould was 26 cases, the ratio was 57.8%,the number of detected Helicobacter pylori was 34 cases,the ratio was 75.6%;in chronic atrophic gastritis,the number of detected mould was 0,the number of detected Helicobacter pylori was 12 cases,the ratio was 26.7%.The Helicobacter pylori detection and mold detection rate of the two groups were statistically significantly different(P<0.05).Conclusion Mould,Helicobacter pylori infection are both gastric cancer inducing pathogens.