CAJ | 학술논문

目的：探讨 Rh 血型系统在恶性血液病中分布特点及相关性。方法采用血清免疫学方法对140例恶性血液病患者进行 Rh 血型系统表型鉴定并对其表型分布进行统计学分析。结果健康对照组 Rh 血型系统表型分布频率从高到低依次是 CCDee ＞ CcDEe ＞ CCDEe ＞ ccDEE ＞ ccDEe ＞ CcDee ＞ CcDEE ＞ ccDee ＝ CCDEE ，血液肿瘤组与健康对照组表型分布趋势不相一致，构成比差异有统计学意义（P＜0．05），CcDee 分布频率在健康对照组和血液肿瘤组间比较差异有统计学意义，相对危险度比值较高（OR ＝2．99）；CCDee 表型相对危险度比值较低（OR ＝0．61）。结论 Rh 血型与恶性血液病的发生有一定关系，CcDee 表型比较容易患恶性血液病，CCDee 表型患恶性血液病风险明显低于 Rh 血型系统其他表型。
목적：탐토 Rh 혈형계통재악성혈액병중분포특점급상관성。방법채용혈청면역학방법대140례악성혈액병환자진행 Rh 혈형계통표형감정병대기표형분포진행통계학분석。결과건강대조조 Rh 혈형계통표형분포빈솔종고도저의차시 CCDee ＞ CcDEe ＞ CCDEe ＞ ccDEE ＞ ccDEe ＞ CcDee ＞ CcDEE ＞ ccDee ＝ CCDEE ，혈액종류조여건강대조조표형분포추세불상일치，구성비차이유통계학의의（P＜0．05），CcDee 분포빈솔재건강대조조화혈액종류조간비교차이유통계학의의，상대위험도비치교고（OR ＝2．99）；CCDee 표형상대위험도비치교저（OR ＝0．61）。결론 Rh 혈형여악성혈액병적발생유일정관계，CcDee 표형비교용역환악성혈액병，CCDee 표형환악성혈액병풍험명현저우 Rh 혈형계통기타표형。
Objective To investigate the distribution characteristics and correlation of Rh blood group system in malignant hemopathy .Methods The Rh blood phenotype identification in 140 patients with malignant hemopathy was performed by using the serological method and its phenotype distribution was statistically analyzed .Results The distribution frequency of Rh blood group phenotypes in the normal control group from high to low in turns was CCDee > CcDEe > CCDEe > ccDEE > ccDEe > CcDee > CcDEE > ccDee = CCDEE ;the distribution trend of Rh blood group phenotypes was significantly different between the malignant hemopathy patients and controls ,the differences were statistically significant (P< 0 .05) ,the distribution frequency of CcDee type had statistically significant differ‐ence between the hemopathy group and the control group ,the relative risk ratio of CcDee type person suffering from malignant hemopathy was higher(OR = 2 .99) and the relative risk ratio that CCDee type person suffering from ma‐lignant hemopathy was lower(OR= 0 .61) .Conclusion There is certain relationship between the occurrence of malig‐nant hemopathy and the Rh blood group .CcDee phenotype person is liable to suffer from malignant hemopathy ,the risk of CCDee type person suffering from malignant hemopathy is lower than that of other Rh group phenotypes .