CAJ | 학술논문

目的研究肾结石患者的身体质量指数(BMI)和24h尿液化学成分之间的关系.方法收集220例肾结石患者的尿液进行24h尿化学成分分析.利用四分位法,分别将男女患者按照BMI进行分层.使用单因素方差分析法和多重线性回归分析法,分析BMI和24h尿液化学成分各数值间的相互关系.结果单因素方差分析结果显示,在男性患者中,BMI的增加与尿钠、钙、柠檬酸、尿酸、镁、草酸钙的增加呈正比例关系,与pH值的下降呈反比例关系.在女性患者中,BMI与尿钠、尿酸、草酸的增加呈正比例关系,与pH值的下降呈反比例关系.多重线性回归分析显示:在男性患者中,BMI与尿钠、草酸钙的增加以及pH值的降低呈正比例关系;在女性患者中,BMI和尿钠、肌酐、磷酸盐、柠檬酸以及硫酸盐呈正比例关系,与尿柠檬酸、硫酸盐呈反比关系.结论本研究的结果显示,BMI的增加和许多肾结石患病风险因素有显著相关性,包括:男性患者中增加的尿钠和尿酸、降低的pH;女性患者中升高的尿酸、尿钠和降低的尿柠檬酸.建议肾结石患者积极减肥、低盐饮食、少食动物蛋白.
목적 연구신결석환자적신체질량지수(BMI)화24h뇨액화학성분지간적관계.방법 수집220례신결석환자적뇨액진행24h뇨화학성분분석.이용사분위법,분별장남녀환자안조BMI진행분층.사용단인소방차분석법화다중선성회귀분석법,분석BMI화24h뇨액화학성분각수치간적상호관계.결과 단인소방차분석결과현시,재남성환자중,BMI적증가여뇨납、개、저몽산、뇨산、미、초산개적증가정정비례관계,여pH치적하강정반비례관계.재녀성환자중,BMI여뇨납、뇨산、초산적증가정정비례관계,여pH치적하강정반비례관계.다중선성회귀분석현시:재남성환자중,BMI여뇨납、초산개적증가이급pH치적강저정정비례관계;재녀성환자중,BMI화뇨납、기항、린산염、저몽산이급류산염정정비례관계,여뇨저몽산、류산염정반비관계.결론 본연구적결과현시,BMI적증가화허다신결석환병풍험인소유현저상관성,포괄:남성환자중증가적뇨납화뇨산、강저적pH;녀성환자중승고적뇨산、뇨납화강저적뇨저몽산.건의신결석환자적겁감비、저염음식、소식동물단백.
Objectives To assess the relationship between the body mass index(BMI) and 24-hour urine chemical composition in the population of kidney stone patients.Methods To collect and analysis 220 cases of kidney stone patients'24-hour urine.Patients were divided into quartiles of body mass index and stratified by gender.Using bivariate and multivariate linear regression explored the relationship between body mass index(BMI) and urine parameters.Results The bivariate analysis shows that BMI increased with urinary sodium,calcium,citrate,uric acid,magnesium,calcium oxalate,uric acid increased significantly correlated,pH value decreased with a significant negative correlation in men.BMI was associated with significantly increased urinary sodium,uric acid,oxalic acid increased significantly positively correlated,pH decreased with a significant negative correlation in women.The multivariate linear regression's results confirmed that BMI was associated only with increases in sodium and calcium oxalate and decrease in pH in men.In women,multivariate analysis demonstrated positive association between BMI and urine sodium,creatinine,and phosphate and a negative relationship with urine citrate and sulfate.Conclusions The results of this study show that the BMI increases and risk factors of kidney stone was significantly correlated,including:increased urinary sodium and uric acid,reduced pH in men;increasing urine uric acid,sodium,and decreasing urine citrate in women.Recommended in patients with urinary calculus actively lose weight,low -salt diet,and low animal protein diet.