CAJ | 학술논문

妊娠合并糖尿病对胎儿心脏结构、功能均可产生不良影响. 这些影响或出生后可逐渐恢复正常,或持续存在至儿童期甚至成年期. 妊娠期糖尿病( GDM)会造成胎儿心脏功能损害,若血糖控制良好将延缓这一损伤,但不能降低损伤程度. 孕前糖尿病母亲血糖控制不良将使先天性心脏病( CHD)的发生风险大幅增加. 通过对影响机制的研究或可预防子代心脏损伤的发生. 超声心动图是目前评估胎儿心脏结构及功能的最佳方法,由于胎儿及新生儿心脏结构及功能有其特殊性,新的评价指标有待被提出. 该文就近年来国内外有关妊娠合并糖尿病对子代心血管系统影响的最新研究进展进行综述.
임신합병당뇨병대태인심장결구、공능균가산생불량영향. 저사영향혹출생후가축점회복정상,혹지속존재지인동기심지성년기. 임신기당뇨병( GDM)회조성태인심장공능손해,약혈당공제량호장연완저일손상,단불능강저손상정도. 잉전당뇨병모친혈당공제불량장사선천성심장병( CHD)적발생풍험대폭증가. 통과대영향궤제적연구혹가예방자대심장손상적발생. 초성심동도시목전평고태인심장결구급공능적최가방법,유우태인급신생인심장결구급공능유기특수성,신적평개지표유대피제출. 해문취근년래국내외유관임신합병당뇨병대자대심혈관계통영향적최신연구진전진행종술.
Gestational diabetes mellitus(GDM)has negative impact on fetal cardiac structure and function.These effects can gradually return to normal after birth or continue till childhood even adulthood.Damage of fetal heart function can be delayed by good controlling glucose, but the degree of the damage cannot be reduced.Poor-controlled glucose in pregnant diabetes will lead to great increasing risk of congenital heart disease ( CHD) .Based on the research of influencing mechanism, the occurrence of heart damage on the offspring can be prevented in the future.Up to now, echocardiography is the best way to assess fetal cardiac structure and function.As fetal and neonatal cardiac structure and function have their particularity, new evaluation indexes need to be put forward.The article reviewed the research progress in impact of GDM on cardiovascular system of offspring both at home and abroad in recent years.