中国继续医学教育
中國繼續醫學教育
중국계속의학교육
China Continuing Medical Education
2015年
23期
132-133
,共2页
辛伐他汀%阿司匹林%脑梗死复发
辛伐他汀%阿司匹林%腦梗死複髮
신벌타정%아사필림%뇌경사복발
Simvastatin%Aspirin%Relapse of cerebral infarction
目的 研究辛伐他汀联合阿司匹林预防脑梗死复发的作用,为临床应用提供依据.方法 将68名脑梗死患者随机分为两组,两组患者均采用常规治疗及检测方案,对照组每晚睡前口服阿司匹林肠溶片;观察组在此基础上每晚睡前服用辛伐他汀片和阿司匹林肠溶片,并进行长期随访.结果 治疗120天后观察组血脂水平开始改善且伴随着服药时间的增加血脂代谢也随之改善;观察组较治疗前其治疗后CHOL、TG及LDL-C降低,HDL-CP升高,P<0.05,差异具有统计学意义;对照组其治疗前后血脂水平及血脂代谢功能无显著性变化, P>0.05,差异不具有统计学意义;观察组脑梗死复发率低于对照组, P<0.05,差异具有统计学意义.结论 辛伐他汀联合阿司匹林可以有效抑制患者的脑梗死复发.
目的 研究辛伐他汀聯閤阿司匹林預防腦梗死複髮的作用,為臨床應用提供依據.方法 將68名腦梗死患者隨機分為兩組,兩組患者均採用常規治療及檢測方案,對照組每晚睡前口服阿司匹林腸溶片;觀察組在此基礎上每晚睡前服用辛伐他汀片和阿司匹林腸溶片,併進行長期隨訪.結果 治療120天後觀察組血脂水平開始改善且伴隨著服藥時間的增加血脂代謝也隨之改善;觀察組較治療前其治療後CHOL、TG及LDL-C降低,HDL-CP升高,P<0.05,差異具有統計學意義;對照組其治療前後血脂水平及血脂代謝功能無顯著性變化, P>0.05,差異不具有統計學意義;觀察組腦梗死複髮率低于對照組, P<0.05,差異具有統計學意義.結論 辛伐他汀聯閤阿司匹林可以有效抑製患者的腦梗死複髮.
목적 연구신벌타정연합아사필림예방뇌경사복발적작용,위림상응용제공의거.방법 장68명뇌경사환자수궤분위량조,량조환자균채용상규치료급검측방안,대조조매만수전구복아사필림장용편;관찰조재차기출상매만수전복용신벌타정편화아사필림장용편,병진행장기수방.결과 치료120천후관찰조혈지수평개시개선차반수착복약시간적증가혈지대사야수지개선;관찰조교치료전기치료후CHOL、TG급LDL-C강저,HDL-CP승고,P<0.05,차이구유통계학의의;대조조기치료전후혈지수평급혈지대사공능무현저성변화, P>0.05,차이불구유통계학의의;관찰조뇌경사복발솔저우대조조, P<0.05,차이구유통계학의의.결론 신벌타정연합아사필림가이유효억제환자적뇌경사복발.
Objective Study clinical application of simvastatin combine aspirin to avert relapse of cerebral infarction, to provide basis in clinical. Methods Selected 68 patients with cerebral infarction were randomly divided into two groups, the control group before gone to bed every night oral aspirin and the observation group additional took simvastatin, and follow-up timely.Results After 120 days cure observation group whose blood lipid levels and blood lipid metabolism improved; After treatment, the observation group`s CHOL, TG, LDL-C were lower and HDL-C was increased,P<0.05, had difference statistically signiifcance. The control group lipid levels and blood lipid metabolism have no changes,P>0.05, had no difference statistically significance, the observation group with cerebral infarction relapse rate was lower than the control group,P<0.05, had difference statistically significance. Conclusion Simvastatin combine aspirin can effectively restrain patients with relapse cerebral infarction.
