国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
International Journal of Laboratory Medicine
2015年
17期
2487-2489
,共3页
邓朝晖%梁梦洁%宋颖博%宋雪%易卫东%鹿新红%张新
鄧朝暉%樑夢潔%宋穎博%宋雪%易衛東%鹿新紅%張新
산조휘%량몽길%송영박%송설%역위동%록신홍%장신
参考区间%参考个体%验证
參攷區間%參攷箇體%驗證
삼고구간%삼고개체%험증
reference interval%reference individual%verification
目的:应用汉族和维吾尔族(维族)体检对象血清TP、ALB、ALT、AST、ALP和GGT检测结果,验证参考区间行业标准(WS/T404.1‐2012及WS/T404.2‐2012)的临床适用性。方法回顾性研究。收集2013年8月至2015年1月在新疆生产建设兵团医院进行乌鲁木齐团体健康体检的汉族和维族(20~79岁)血清TP、ALB、ALT、AST、ALP和GGT检测结果,依据Sta‐land建议的医学决定水平2剔除有明显异常的体检人群(GGT按其建议的参考上限两倍取值)。按照参考区间行业标准的分组,统计汉族和维族各项目检测结果P2.5~P97.5,并计算超出参考区间行业标准的例数所占比例。验证的判断标准:超出例数低于10%则通过验证。结果正态性检验结果表明汉族和维族参考个体各项目的统计数据均呈偏态分布。汉族和维族参考个体各项目检测结果P2.5~P97.5:TP(汉族65~81 g/L、维族64~81 g/L),ALB(汉族41~53 g/L、维族40~52 g/L),ALT男性(汉族9~51 U/L、维族9~53 U/L),ALT女性(汉族7~42 U/L、维族6~43 U/L),AST男性(汉族14~42 U/L、维族12~42 U/L),AST女性(汉族12~37 U/L、维族12~38 U/L ),A L P男性(汉族45~119 U/L、维族47~122 U/L ),A L P女性20~49岁(汉族35~95 U/L、维族40~104 U/L),ALP女性50~79岁(汉族43~131 U/L、维族51~132 U/L),GGT男性(汉族11~71 U/L、维族11~73 U/L),GGT女性(汉族8~54 U/L、维族7~55 U/L)。汉族男性、维族男性和女性参考个体血清AST检测结果在参考区间行业标准之外的比例略超出10%,但超出比例以低于A S T行业标准下限值的比例为主,其余项目的汉族和维族参考个体检测结果超出行业标准的比例均在10%以内。结论参考区间行业标准(WS/T404.1‐2012及WS/T404.2‐2012)适用于本实验室检测的汉族和维族人群。
目的:應用漢族和維吾爾族(維族)體檢對象血清TP、ALB、ALT、AST、ALP和GGT檢測結果,驗證參攷區間行業標準(WS/T404.1‐2012及WS/T404.2‐2012)的臨床適用性。方法迴顧性研究。收集2013年8月至2015年1月在新疆生產建設兵糰醫院進行烏魯木齊糰體健康體檢的漢族和維族(20~79歲)血清TP、ALB、ALT、AST、ALP和GGT檢測結果,依據Sta‐land建議的醫學決定水平2剔除有明顯異常的體檢人群(GGT按其建議的參攷上限兩倍取值)。按照參攷區間行業標準的分組,統計漢族和維族各項目檢測結果P2.5~P97.5,併計算超齣參攷區間行業標準的例數所佔比例。驗證的判斷標準:超齣例數低于10%則通過驗證。結果正態性檢驗結果錶明漢族和維族參攷箇體各項目的統計數據均呈偏態分佈。漢族和維族參攷箇體各項目檢測結果P2.5~P97.5:TP(漢族65~81 g/L、維族64~81 g/L),ALB(漢族41~53 g/L、維族40~52 g/L),ALT男性(漢族9~51 U/L、維族9~53 U/L),ALT女性(漢族7~42 U/L、維族6~43 U/L),AST男性(漢族14~42 U/L、維族12~42 U/L),AST女性(漢族12~37 U/L、維族12~38 U/L ),A L P男性(漢族45~119 U/L、維族47~122 U/L ),A L P女性20~49歲(漢族35~95 U/L、維族40~104 U/L),ALP女性50~79歲(漢族43~131 U/L、維族51~132 U/L),GGT男性(漢族11~71 U/L、維族11~73 U/L),GGT女性(漢族8~54 U/L、維族7~55 U/L)。漢族男性、維族男性和女性參攷箇體血清AST檢測結果在參攷區間行業標準之外的比例略超齣10%,但超齣比例以低于A S T行業標準下限值的比例為主,其餘項目的漢族和維族參攷箇體檢測結果超齣行業標準的比例均在10%以內。結論參攷區間行業標準(WS/T404.1‐2012及WS/T404.2‐2012)適用于本實驗室檢測的漢族和維族人群。
목적:응용한족화유오이족(유족)체검대상혈청TP、ALB、ALT、AST、ALP화GGT검측결과,험증삼고구간행업표준(WS/T404.1‐2012급WS/T404.2‐2012)적림상괄용성。방법회고성연구。수집2013년8월지2015년1월재신강생산건설병단의원진행오로목제단체건강체검적한족화유족(20~79세)혈청TP、ALB、ALT、AST、ALP화GGT검측결과,의거Sta‐land건의적의학결정수평2척제유명현이상적체검인군(GGT안기건의적삼고상한량배취치)。안조삼고구간행업표준적분조,통계한족화유족각항목검측결과P2.5~P97.5,병계산초출삼고구간행업표준적례수소점비례。험증적판단표준:초출례수저우10%칙통과험증。결과정태성검험결과표명한족화유족삼고개체각항목적통계수거균정편태분포。한족화유족삼고개체각항목검측결과P2.5~P97.5:TP(한족65~81 g/L、유족64~81 g/L),ALB(한족41~53 g/L、유족40~52 g/L),ALT남성(한족9~51 U/L、유족9~53 U/L),ALT녀성(한족7~42 U/L、유족6~43 U/L),AST남성(한족14~42 U/L、유족12~42 U/L),AST녀성(한족12~37 U/L、유족12~38 U/L ),A L P남성(한족45~119 U/L、유족47~122 U/L ),A L P녀성20~49세(한족35~95 U/L、유족40~104 U/L),ALP녀성50~79세(한족43~131 U/L、유족51~132 U/L),GGT남성(한족11~71 U/L、유족11~73 U/L),GGT녀성(한족8~54 U/L、유족7~55 U/L)。한족남성、유족남성화녀성삼고개체혈청AST검측결과재삼고구간행업표준지외적비례략초출10%,단초출비례이저우A S T행업표준하한치적비례위주,기여항목적한족화유족삼고개체검측결과초출행업표준적비례균재10%이내。결론삼고구간행업표준(WS/T404.1‐2012급WS/T404.2‐2012)괄용우본실험실검측적한족화유족인군。
Objective To verify the clinical applicability of the published standard intervals of routine clinical chemistry (WS/T404 .1‐2012 ,WS/T404 .2‐2012) based on the health examination results of Han and Uygur populations in Urumqi .Methods This was a retrospective study .The results of serum TP ,ALB ,ALT ,AST ,ALP ,GGT from healthy examination individuals of Han and Uygur populations (from 2013 August to 2015 January) were collected and the healthy cases (age range:20 -79 years old) were chosen to calculate the 2 .5% and 97 .5% percentiles ,excluding the significant abnormal results according to the Medical Deciding Level 2 recommended by Staland .The percents of health cases not falling in the published standard interval were calculated to meet the judgment criterion of verification (<10% ) .Results The test of normality revealed that the Han and Uygur's results of all veri‐fied items were skewed distributions .The 2 .5% and 97 .5% percentiles of the results of two populations were as follows ,TP(Han 65 -81 g/L ;Uygur 64-81 g/L) ,ALB(Han 41-53 g/L ;Uygur 40-52 g/L) ,ALT(Han:male 9-51 U/L and female 7-42 U/L ;Uygur:male 9-53 U/L and female 6-43 U/L) ,AST(Han:male 14-42 U/L and female 12-37 U/L ,Uygur:male 12-42 U/L and female 12-38 U/L) ,ALP(Han:male 45-119 U/L ;Uygur:male 47-122 U/L) ,ALP(female 20-49 years old:Han 35-95 U/L and Uygur 40-104 U/L) ,ALP(female 50-79 years old:Han 43-131 U/L and Uygur 51-132 U/L) ,GGT(Han:male 11-71 U/L and female 8-54 U/L ;Uygur :male 11 -73 U/L and female 7 -55 U/L ) .The percents of AST results for Han's male , Uygur's male and Uygur's female not falling in the published standard reference interval were slightly over 10% ,but AST results o‐ver 10% were mainly under the lower limit of the published standard reference interval .The health case percents for the other veri‐fied items of Han and Uygur populations not falling in the published standard reference interval were under 10% .Conclusion The published standard reference intervals of routine clinical chemistry (WS/T404 .1‐2012 ,WS/T404 .2‐2012) are applicable in our la‐boratory for the detection of Han and Uygur population .