医学综述
醫學綜述
의학종술
Medical Recapitulate
2015年
16期
2997-2999
,共3页
李情(综述)%许爱娥(审校)
李情(綜述)%許愛娥(審校)
리정(종술)%허애아(심교)
白癜风%中药%动物模型
白癜風%中藥%動物模型
백전풍%중약%동물모형
Vitiligo%Chinese herbs%Animal model
白癜风是一种常见的获得性的以局部或全身皮肤黏膜色素脱失为特征的皮肤病，直接影响患者的容貌，进而影响患者生活质量。白癜风的发病机制不清，存在多种学说如黑素细胞自毁、自身免疫、遗传缺陷、氧化应激、微量元素失衡等，但最终结果是黑素细胞减少、缺失和功能抑制。所以，黑素细胞的损害在白癜风的病机中占重要地位。中药治疗白癜风有确切疗效。借助于其他学科，中药治疗白癜风已研究至分子机制。
白癜風是一種常見的穫得性的以跼部或全身皮膚黏膜色素脫失為特徵的皮膚病，直接影響患者的容貌，進而影響患者生活質量。白癜風的髮病機製不清，存在多種學說如黑素細胞自燬、自身免疫、遺傳缺陷、氧化應激、微量元素失衡等，但最終結果是黑素細胞減少、缺失和功能抑製。所以，黑素細胞的損害在白癜風的病機中佔重要地位。中藥治療白癜風有確切療效。藉助于其他學科，中藥治療白癜風已研究至分子機製。
백전풍시일충상견적획득성적이국부혹전신피부점막색소탈실위특정적피부병，직접영향환자적용모，진이영향환자생활질량。백전풍적발병궤제불청，존재다충학설여흑소세포자훼、자신면역、유전결함、양화응격、미량원소실형등，단최종결과시흑소세포감소、결실화공능억제。소이，흑소세포적손해재백전풍적병궤중점중요지위。중약치료백전풍유학절료효。차조우기타학과，중약치료백전풍이연구지분자궤제。
Vitiligo is a common acquired skin disease with topical or systemic depigmentation .It impacts the patients′appearence,thereby affecting their life quality.The etiology and pathogenesis of vitiligo have not yet been fully elucidated.There are many theories such as melanocytes self-destruction,autoimmune,genetic defects,oxidative stress,microelements imbalance,etc.,but the end results are melanocytes number reduction, missing and function inhibition.Melanocyte damage plays an important role in the pathogenesis of vitiligo.Chi-nese medicine treatment of vitiligo has an affirmative effect.With the development of other subjects,the study of TCM treatment for vitiligo has reached the molecular level.
