CAJ | 학술논문

目的：研究复方前列安颗粒治疗慢性无菌性前列腺炎大鼠的药效学。方法按照体重随机将大鼠分为3组，实验组（给予3．0 g? kg－1复方前列安颗粒）、对照组（给予2．4 g? kg－1前列舒乐颗粒）及正常组（给予蒸馏水），每日1次。给药7d后，镜下观察大鼠白细胞计数、卵磷脂小体密度的差异，用左、右耳片重量之差计算肿胀度，比较深入腹腔染料量的差异。结果实验组，白细胞数明显低于对照组和正常组，卵磷脂小体密度明显高于对照组和正常组（均P＜0．05）；实验组、对照组与正常组的肿胀度和光密度比较，差异有统计学意义（ P＜0．05）。结论复方前列安颗粒对慢性无菌性前列腺炎症具有良好的抑制作用。
목적：연구복방전렬안과립치료만성무균성전렬선염대서적약효학。방법안조체중수궤장대서분위3조，실험조（급여3．0 g? kg－1복방전렬안과립）、대조조（급여2．4 g? kg－1전렬서악과립）급정상조（급여증류수），매일1차。급약7d후，경하관찰대서백세포계수、란린지소체밀도적차이，용좌、우이편중량지차계산종창도，비교심입복강염료량적차이。결과실험조，백세포수명현저우대조조화정상조，란린지소체밀도명현고우대조조화정상조（균P＜0．05）；실험조、대조조여정상조적종창도화광밀도비교，차이유통계학의의（ P＜0．05）。결론복방전렬안과립대만성무균성전렬선염증구유량호적억제작용。
Objective To explore the efficacy of Compound Qianliean Granule in the treatment of chronic nonbacterial prostatitis study in rats. Methods The rats were randomly divided into three groups, experimental group ( treated with 3.0 g? kg -1 Compound Qianliean Granule ) and control group ( treated with 2.4 g? kg-1 Qianlieshule granule ) and normal group ( treated with distilled water ) , 1 times daily. The difference of white blood cell count, lecithin corpuscle density were observed after 7 days administration by microscope.The difference of left and right ear weight was calculated on the degree of swelling. The differences of quantity in abdominal cavity dye of relatively deep was compared.Results The white blood cell count in experimental group was significantly higher than that of the control group and the normal group.The lecithin corpuscle density as compared with the control group and the normal group, the difference is statistically significant (P<0.05).The difference of swelling degree and the absorbance compared between experimental group, control group and normal group were significant ( P<0.05).Conclusion Compound Qianliean Granule has good inhibitory effect on chronic abacterial prostatitis.