CAJ | 학술논문

目的：探讨不同孕期孕妇D-二聚体（D-D）、维生素B12、血清同型半胱氨酸（HCY）与妊娠高血压疾病（PIH）之间的关系。方法：选取在我院进行产检的孕妇287例为研究对象，其中PIH孕妇86例，正常妊娠孕妇201例，根据孕期对不同孕妇血清D-D、维生素B12、HCY水平进行检测。结果：PIH组与正常妊娠组比较，孕中期及孕晚期血清HCY水平与D-D水平明显升高（P＜0.05），且在孕中期及孕晚期，PIH组及正常妊娠组孕妇血清HCY水平与D-D水平呈正相关，而与维生素B12均无相关性。结论：在孕中晚期进行HCY水平及D-D水平检测可作为预测PIH的一个重要的危险因素。
목적：탐토불동잉기잉부D-이취체（D-D）、유생소B12、혈청동형반광안산（HCY）여임신고혈압질병（PIH）지간적관계。방법：선취재아원진행산검적잉부287례위연구대상，기중PIH잉부86례，정상임신잉부201례，근거잉기대불동잉부혈청D-D、유생소B12、HCY수평진행검측。결과：PIH조여정상임신조비교，잉중기급잉만기혈청HCY수평여D-D수평명현승고（P＜0.05），차재잉중기급잉만기，PIH조급정상임신조잉부혈청HCY수평여D-D수평정정상관，이여유생소B12균무상관성。결론：재잉중만기진행HCY수평급D-D수평검측가작위예측PIH적일개중요적위험인소。
Objective:To evaluate the Relationship between the serum levels of homocysteine, D-dimer, vitamin B12 and pregnancy-induced hypertension in different pregnancies. Methods:287 pregnant women who registered for prenatal examination of pregnant in the hospital were selected as research subjects. And there were 86 cases of PIH and 201 cases of normal pregnancy among them. The serum levels of homocysteine, D-dimer, vitamin B12 were detected according to different pregnancy.Results:Compared with normal pregnancy group, the serum HCY and D-D level of PIH group significantly increased in medium and late pregnancy periods (P<0.05).In mid and late pregnancy periods, the serum HCY levels of PIH group and normal pregnant group positive correlated with serum D-D levels(P<0.05),and did not correlate with vitamin B12 levels(P>0.05). Conclusions:n middle and late pregnancy periods, to detect the levels of HCY and D-D be an improtant risk factor of PIH.