中国实用护理杂志
中國實用護理雜誌
중국실용호리잡지
Chinese Journal of Practical Nursing
2015年
24期
1852-1856
,共5页
李婷婷%关风光%华筱娟%何文静
李婷婷%關風光%華篠娟%何文靜
리정정%관풍광%화소연%하문정
阻塞性睡眠呼吸暂停%口外牵引器%系统评价
阻塞性睡眠呼吸暫停%口外牽引器%繫統評價
조새성수면호흡잠정%구외견인기%계통평개
Obstructive sleep apnea hypopnea%Oral appliance%Systematic review
目的 评价可调式口腔矫治器(oral appliance,OA)对阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)患者通气情况的影响.方法 电子检索数据库自1990年1月至2014年7月国内外口腔矫治器对OSAHS患者通气情况影响的随机对照试验.采用RevMan5.2软件进行数据合并分析.无法转换合并的数据采用描述性分析.结果 共纳入6个随机对照试验,共1 109例患者,包括4个随机平行对照试验和2个随机交叉对照试验.Meta分析结果显示,可调式口腔矫治器有利于改善患者的睡眠呼吸暂停低通气指数(apnea-hypopnea index,AHI),固定效应模型,加权均数差(WMD)=-2.38,95％可信区间(CI)-359～-1.17,P＜0.01,提高最低血氧饱和度SaO2,随机效应模型,WMD=3.09,95％CI1.16～5.02,P＜0.01.由于睡眠评分数据类型不同无法合并,故采用描述性分析,结果显示数据差异无统计学意义.结论 可调式口腔矫治器更有利于降低AHI,提高最低(SaO2),但睡眠评分无明显的改善,需设计更多大样本、多中心随机对照试验,以对可调式口腔矫治器的综合效果进行验证.
目的 評價可調式口腔矯治器(oral appliance,OA)對阻塞性睡眠呼吸暫停低通氣綜閤徵(obstructive sleep apnea hypopnea syndrome,OSAHS)患者通氣情況的影響.方法 電子檢索數據庫自1990年1月至2014年7月國內外口腔矯治器對OSAHS患者通氣情況影響的隨機對照試驗.採用RevMan5.2軟件進行數據閤併分析.無法轉換閤併的數據採用描述性分析.結果 共納入6箇隨機對照試驗,共1 109例患者,包括4箇隨機平行對照試驗和2箇隨機交扠對照試驗.Meta分析結果顯示,可調式口腔矯治器有利于改善患者的睡眠呼吸暫停低通氣指數(apnea-hypopnea index,AHI),固定效應模型,加權均數差(WMD)=-2.38,95％可信區間(CI)-359～-1.17,P＜0.01,提高最低血氧飽和度SaO2,隨機效應模型,WMD=3.09,95％CI1.16～5.02,P＜0.01.由于睡眠評分數據類型不同無法閤併,故採用描述性分析,結果顯示數據差異無統計學意義.結論 可調式口腔矯治器更有利于降低AHI,提高最低(SaO2),但睡眠評分無明顯的改善,需設計更多大樣本、多中心隨機對照試驗,以對可調式口腔矯治器的綜閤效果進行驗證.
목적 평개가조식구강교치기(oral appliance,OA)대조새성수면호흡잠정저통기종합정(obstructive sleep apnea hypopnea syndrome,OSAHS)환자통기정황적영향.방법 전자검색수거고자1990년1월지2014년7월국내외구강교치기대OSAHS환자통기정황영향적수궤대조시험.채용RevMan5.2연건진행수거합병분석.무법전환합병적수거채용묘술성분석.결과 공납입6개수궤대조시험,공1 109례환자,포괄4개수궤평행대조시험화2개수궤교차대조시험.Meta분석결과현시,가조식구강교치기유리우개선환자적수면호흡잠정저통기지수(apnea-hypopnea index,AHI),고정효응모형,가권균수차(WMD)=-2.38,95％가신구간(CI)-359～-1.17,P＜0.01,제고최저혈양포화도SaO2,수궤효응모형,WMD=3.09,95％CI1.16～5.02,P＜0.01.유우수면평분수거류형불동무법합병,고채용묘술성분석,결과현시수거차이무통계학의의.결론 가조식구강교치기경유리우강저AHI,제고최저(SaO2),단수면평분무명현적개선,수설계경다대양본、다중심수궤대조시험,이대가조식구강교치기적종합효과진행험증.
Objective To evaluate the efficacy of adjustable oral appliance (OA) on ventilation of patients with obstructive sleep apnea hypopnea syndrome (OSAHS).Methods Databases were searched from Junuary 1990 to July 2014 for randomized controlled trials on the use of adjustable OA for the promotion of ventilation in OSAHS.Meta analysis was performed with RevMan5.2 software,and descriptive analysis of the data that could not be converted and merged was performed.Results Totally 6 RCTs involved,including 1 109 patients,which involved 4 random parallel controlled trials and 2 random crossover controlled trials.Meta-analysis showed that adjustable OA were associated with a decreased apnea-hypopnea index(AHI) [fixed effect model,WMD=-2.38,95％CI (-3.59--1.17),P＜0.01] and an improvement in minimum arterial oxygen saturation (SaO2)[randomized effect model,WMD=3.09,95％CI(1.16-5.02),P＜0.01] of OSAHS patients.The descriptive analysis showed that the difference in the sleep score was not statistically significant because the data could not be converted.Conclusions Compared to fixed oral appliance,adjustable oral appliance produced greater effect in reduction of AHI and the improvement in minimum SaO2,but the sleep score is not improved significantly,the large sample and multi-center randomized controlled test needs to be designed for the verification of comprehensive effect of adjustable oral appliance.
