实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
2015年
7期
111-114
,共4页
冠心病%心绞痛%复方丹芪注射液%气虚血瘀%治疗结果
冠心病%心絞痛%複方丹芪註射液%氣虛血瘀%治療結果
관심병%심교통%복방단기주사액%기허혈어%치료결과
Coronary disease%Angina pectoris%Compound danqi injection%Qi-deficiency blood stasis%Treatment outcome
目的：分析复方丹芪注射液治疗气虚血瘀型冠心病心绞痛的临床疗效及安全性。方法选取2013年3月—2014年1月莒南县人民医院心血管内科病房诊治的冠心病心绞痛患者146例，均符合“气虚血瘀型冠心病心绞痛”诊断标准，将患者随机分为治疗组和对照组，各73例。在常规治疗基础上，治疗组患者给予复方丹芪注射液，对照组患者给予丹参注射液，两组患者均以两周为1个疗程。比较两组患者治疗后心绞痛症状和心电图改善情况、治疗前后血流动力学指标及治疗期间不良反应发生情况。结果治疗后治疗组患者心绞痛症状改善情况和心电图改善情况优于对照组（ u值分别为2.509、2.308， P＜0.05）。治疗前两组患者全血高切黏度、全血低切黏度、血浆比黏度、红细胞比容及纤维蛋白原比较，差异均无统计学意义（ P＞0.05）；治疗后治疗组患者上述指标均低于对照组（ P＜0.05）。治疗组有1例患者出现头晕，对照组有2例患者出现腹胀。所有患者治疗前后血尿便常规及肝肾功能指标均在参考范围。结论复方丹芪注射液治疗气虚血瘀型冠心病心绞痛的临床疗效确切，能有效改善患者心绞痛症状和血液流变学，且安全性高。
目的：分析複方丹芪註射液治療氣虛血瘀型冠心病心絞痛的臨床療效及安全性。方法選取2013年3月—2014年1月莒南縣人民醫院心血管內科病房診治的冠心病心絞痛患者146例，均符閤“氣虛血瘀型冠心病心絞痛”診斷標準，將患者隨機分為治療組和對照組，各73例。在常規治療基礎上，治療組患者給予複方丹芪註射液，對照組患者給予丹參註射液，兩組患者均以兩週為1箇療程。比較兩組患者治療後心絞痛癥狀和心電圖改善情況、治療前後血流動力學指標及治療期間不良反應髮生情況。結果治療後治療組患者心絞痛癥狀改善情況和心電圖改善情況優于對照組（ u值分彆為2.509、2.308， P＜0.05）。治療前兩組患者全血高切黏度、全血低切黏度、血漿比黏度、紅細胞比容及纖維蛋白原比較，差異均無統計學意義（ P＞0.05）；治療後治療組患者上述指標均低于對照組（ P＜0.05）。治療組有1例患者齣現頭暈，對照組有2例患者齣現腹脹。所有患者治療前後血尿便常規及肝腎功能指標均在參攷範圍。結論複方丹芪註射液治療氣虛血瘀型冠心病心絞痛的臨床療效確切，能有效改善患者心絞痛癥狀和血液流變學，且安全性高。
목적：분석복방단기주사액치료기허혈어형관심병심교통적림상료효급안전성。방법선취2013년3월—2014년1월거남현인민의원심혈관내과병방진치적관심병심교통환자146례，균부합“기허혈어형관심병심교통”진단표준，장환자수궤분위치료조화대조조，각73례。재상규치료기출상，치료조환자급여복방단기주사액，대조조환자급여단삼주사액，량조환자균이량주위1개료정。비교량조환자치료후심교통증상화심전도개선정황、치료전후혈류동역학지표급치료기간불량반응발생정황。결과치료후치료조환자심교통증상개선정황화심전도개선정황우우대조조（ u치분별위2.509、2.308， P＜0.05）。치료전량조환자전혈고절점도、전혈저절점도、혈장비점도、홍세포비용급섬유단백원비교，차이균무통계학의의（ P＞0.05）；치료후치료조환자상술지표균저우대조조（ P＜0.05）。치료조유1례환자출현두훈，대조조유2례환자출현복창。소유환자치료전후혈뇨편상규급간신공능지표균재삼고범위。결론복방단기주사액치료기허혈어형관심병심교통적림상료효학절，능유효개선환자심교통증상화혈액류변학，차안전성고。
Objective To analyze the clinical effect and safety of compound danqi injection on angina pectoris with qi-deficiency and blood-stasis type of TCM in patients with coronary heart disease.Methods From March 2013 to January 2014, a total of 146 coronary heart disease patients with angina pectoris were selected, all of them were diagnosed as qi -deficiency and blood-stasis type of TCM, and they were randomly divided into treatment group and control group, each of 73 cases.Based on conventional treatment, patients of treatment group were given compound danqi injection, while patients of control group were given danshen injection, both groups treated for 2 weeks as a course.Improvement of angina pectoris symptom and improvement of ECG after treatment, hemodynamic index before and after treatment and incidence of adverse reactions during treatment were compared between the two groups.Results Improvement of angina pectoris symptom and improvement of ECG of treatment group were statistically significantly better than those of control group (u=2.509, 2.308, P<0.05).No statistically significant differences of whole high blood viscosity, whole low blood viscosity, plasma viscosity, hematocrit or fibrinogen was found between the two groups before treatment (P>0.05); while above index of treatment group were statistically significantly lower than those of control group (P<0.05).During treatment, one case of treatment group occurred dizziness, 2 cases of control group occurred abdominal distension.Before and after treatment, routine blood, stool and urine examination results, liver and kidney function indicators of all of the patients were normal.Conclusion Compound danqi injection has certain clinical effect on angina pectoris with qi-deficiency and blood-stasis type of TCM in patients with coronary heart disease, which can effectively relieve angina pectoris symptom and improve hemorheology, with high safety.
