医学综述
醫學綜述
의학종술
Medical Recapitulate
2015年
16期
2981-2983
,共3页
梁大胜(综述)%石齐芳(审校)
樑大勝(綜述)%石齊芳(審校)
량대성(종술)%석제방(심교)
泛耐药%鲍曼氏不动杆菌%药物治疗策略
汎耐藥%鮑曼氏不動桿菌%藥物治療策略
범내약%포만씨불동간균%약물치료책략
Extensively drug-resistant%Acinetobacter baumannii%Medication strategy
鲍曼不动杆菌广泛存在医院环境中,是医院感染的重要条件致病菌,鲍曼不动杆菌耐药率逐年升高,临床上已出现了多重耐药、泛耐药菌株,甚至全耐药菌株。泛耐药鲍曼不动杆菌株是指仅对1~2种对其感染治疗有效的抗菌药物(主要是替加环素和/或多黏菌素)敏感的菌株,其分离率逐年上升,临床上选择抗菌药物和治疗方案非常棘手。该文就泛耐药鲍曼不动杆菌感染治疗的相关问题进行综述。
鮑曼不動桿菌廣汎存在醫院環境中,是醫院感染的重要條件緻病菌,鮑曼不動桿菌耐藥率逐年升高,臨床上已齣現瞭多重耐藥、汎耐藥菌株,甚至全耐藥菌株。汎耐藥鮑曼不動桿菌株是指僅對1~2種對其感染治療有效的抗菌藥物(主要是替加環素和/或多黏菌素)敏感的菌株,其分離率逐年上升,臨床上選擇抗菌藥物和治療方案非常棘手。該文就汎耐藥鮑曼不動桿菌感染治療的相關問題進行綜述。
포만불동간균엄범존재의원배경중,시의원감염적중요조건치병균,포만불동간균내약솔축년승고,림상상이출현료다중내약、범내약균주,심지전내약균주。범내약포만불동간균주시지부대1~2충대기감염치료유효적항균약물(주요시체가배소화/혹다점균소)민감적균주,기분리솔축년상승,림상상선택항균약물화치료방안비상극수。해문취범내약포만불동간균감염치료적상관문제진행종술。
Acinetobacter baumannii is an important opportunistic pathogen and common cause of hospital-acquired infections,which is found widely existing in the environment.The resistance rate of Acinetobacter bawnannii is increasing gradually:multidrug-resistance strains,extensive drug-resistant strains,and even pan drug-resistant strains have been reported.Extensive drug-resistant Acinetobacter baumannii is sensitive only to 1-2 antibiotic drugs(mainly tigecycline and/or polymyxins),and the separation rate has been increasing year by year,which has become a clinical problem of anti-infective therapy.Here is to make a review of the current treatment options for extensive drug-resistant Acinetobacter baumannii infections.