中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
Chinese Journal of Woman and Child Health Research
2015年
4期
840-842
,共3页
血浆置换%格林巴利综合征%疗效%综合干预
血漿置換%格林巴利綜閤徵%療效%綜閤榦預
혈장치환%격림파리종합정%료효%종합간예
plasma exchange ( PE)%Green Barre syndrome ( GBS)%curative effect%comprehensive intervention
目的 观察综合干预对血浆置换( PE)治疗格林巴利综合征( GBS)患儿的疗效和安全性的影响. 方法 回顾性分析2 012年1月至2013年12月在西安市儿童医院住院治疗的54例GBS患儿临床资料,按其治疗时间2012年选取的病例为对照组,2013年为观察组,观察组和对照组各选27例资料完整的病例进行分析. 两组患儿均给予内科综合治疗、PE治疗和基础护理,观察组在对照组基础上对患儿实施预见性综合干预措施,分析两组患儿住院时间、疗效及副反应等. 结果 观察组患儿疗效显著高于对照组,且住院时间短于对照组,异常情况发生率低于对照组,以上指标两组之间比较,差异均有统计学意义(χ2 =7.94,t=2.15,χ2 =14.34;均P<0.05). 结论 综合干预可提高GBS患儿PE治疗的疗效和安全性,缩短患儿住院时间.
目的 觀察綜閤榦預對血漿置換( PE)治療格林巴利綜閤徵( GBS)患兒的療效和安全性的影響. 方法 迴顧性分析2 012年1月至2013年12月在西安市兒童醫院住院治療的54例GBS患兒臨床資料,按其治療時間2012年選取的病例為對照組,2013年為觀察組,觀察組和對照組各選27例資料完整的病例進行分析. 兩組患兒均給予內科綜閤治療、PE治療和基礎護理,觀察組在對照組基礎上對患兒實施預見性綜閤榦預措施,分析兩組患兒住院時間、療效及副反應等. 結果 觀察組患兒療效顯著高于對照組,且住院時間短于對照組,異常情況髮生率低于對照組,以上指標兩組之間比較,差異均有統計學意義(χ2 =7.94,t=2.15,χ2 =14.34;均P<0.05). 結論 綜閤榦預可提高GBS患兒PE治療的療效和安全性,縮短患兒住院時間.
목적 관찰종합간예대혈장치환( PE)치료격림파리종합정( GBS)환인적료효화안전성적영향. 방법 회고성분석2 012년1월지2013년12월재서안시인동의원주원치료적54례GBS환인림상자료,안기치료시간2012년선취적병례위대조조,2013년위관찰조,관찰조화대조조각선27례자료완정적병례진행분석. 량조환인균급여내과종합치료、PE치료화기출호리,관찰조재대조조기출상대환인실시예견성종합간예조시,분석량조환인주원시간、료효급부반응등. 결과 관찰조환인료효현저고우대조조,차주원시간단우대조조,이상정황발생솔저우대조조,이상지표량조지간비교,차이균유통계학의의(χ2 =7.94,t=2.15,χ2 =14.34;균P<0.05). 결론 종합간예가제고GBS환인PE치료적료효화안전성,축단환인주원시간.
Objective To observe the curative effect and safety of comprehensive intervention on children with Green Barry syndrome ( GBS) treated by plasma exchange ( PE) .Methods Retrospective analysis was conducted on the clinical data of 54 children with GBS hospitalized in Xi' an Children' s Hospital during the period of January 2012 to December 2013.Cases treated in 2012 were in control group, and the cases treated in 2013 were in observation group.There were 27 cases in both groups.Two groups of children were given comprehensive internal medication, PE treatment and basic nursing care.The observation group accepted predictive comprehensive intervention based on the treatment for the control group.Statistical analyses were conducted in two groups in the aspects of hospitalization length, curative efficacy and side effects.Results Compared with the control group, the observation group had significantly higher curative effect, shorter hospitalization length and lower incidence of abnormal reaction (χ2 =7.94,t =2.15,χ2 =14.34, all P <0.05). Conclusion Comprehensive intervention can improve the curative efficacy and safety of PE treatment on GBS in children and shorten hospitalization length.
