实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
2015年
7期
33-35,39
,共4页
肺疾病, 慢性阻塞性%睡眠呼吸暂停, 阻塞性%红细胞分布宽度%预测
肺疾病, 慢性阻塞性%睡眠呼吸暫停, 阻塞性%紅細胞分佈寬度%預測
폐질병, 만성조새성%수면호흡잠정, 조새성%홍세포분포관도%예측
Pulmonary disease,chronic obstructive%Sleep apnea,obstructive%Red cell distribution %width%Forecasting
目的：探讨红细胞分布宽度（ RDW）对重叠综合征的预测价值。方法连续收集2013年6月—2015年1月在暨南大学第二临床医学院住院治疗的20例轻度COPD患者（ A组）、20例中重度COPD患者（ B组）、20例轻度重叠综合征患者（ C组）及20例中重度重叠综合征患者（ D组），并根据RDW参考范围将所有患者分为RDW正常组59例和RDW增高组21例。比较A、 B、 C、 D 4组患者一般资料、动脉血气分析指标〔pH值、动脉血氧分压（ PaO2）、动脉血二氧化碳分压（ PaCO2）〕、血浆超敏C反应蛋白（ hs－CRP）水平及RDW；比较RDW正常组与RDW增高组患者一般资料、动脉血气分析指标及血浆hs－CRP水平；并分析RDW与PaO2、血浆hs－CRP水平的相关性。结果4组患者性别、年龄及pH值比较，差异无统计学意义（P＞0.05）； A组和B组患者PaO2高于D组，血浆hs－CRP水平和RDW低于D组， C组患者PaCO2低于D组， A组和B组患者RDW低于C组（P＜0.05）。 RDW正常组与RDW增高组患者性别、年龄、 pH值及PaCO2比较，差异无统计学意义（ P＞0.05）； RDW增高组患者血浆hs－CRP水平高于RDW正常组、 PaO2低于RDW正常组（P＜0.05）。 Pearson相关分析结果显示， RDW与PaO2呈负相关（r＝－0.265， P＝0.018），与血浆hs－CRP水平呈正相关（r＝0.258， P＝0.021）。结论 RDW可用于重叠综合征患者炎症及气道病变严重程度的初步评估，具有一定的预测价值。
目的：探討紅細胞分佈寬度（ RDW）對重疊綜閤徵的預測價值。方法連續收集2013年6月—2015年1月在暨南大學第二臨床醫學院住院治療的20例輕度COPD患者（ A組）、20例中重度COPD患者（ B組）、20例輕度重疊綜閤徵患者（ C組）及20例中重度重疊綜閤徵患者（ D組），併根據RDW參攷範圍將所有患者分為RDW正常組59例和RDW增高組21例。比較A、 B、 C、 D 4組患者一般資料、動脈血氣分析指標〔pH值、動脈血氧分壓（ PaO2）、動脈血二氧化碳分壓（ PaCO2）〕、血漿超敏C反應蛋白（ hs－CRP）水平及RDW；比較RDW正常組與RDW增高組患者一般資料、動脈血氣分析指標及血漿hs－CRP水平；併分析RDW與PaO2、血漿hs－CRP水平的相關性。結果4組患者性彆、年齡及pH值比較，差異無統計學意義（P＞0.05）； A組和B組患者PaO2高于D組，血漿hs－CRP水平和RDW低于D組， C組患者PaCO2低于D組， A組和B組患者RDW低于C組（P＜0.05）。 RDW正常組與RDW增高組患者性彆、年齡、 pH值及PaCO2比較，差異無統計學意義（ P＞0.05）； RDW增高組患者血漿hs－CRP水平高于RDW正常組、 PaO2低于RDW正常組（P＜0.05）。 Pearson相關分析結果顯示， RDW與PaO2呈負相關（r＝－0.265， P＝0.018），與血漿hs－CRP水平呈正相關（r＝0.258， P＝0.021）。結論 RDW可用于重疊綜閤徵患者炎癥及氣道病變嚴重程度的初步評估，具有一定的預測價值。
목적：탐토홍세포분포관도（ RDW）대중첩종합정적예측개치。방법련속수집2013년6월—2015년1월재기남대학제이림상의학원주원치료적20례경도COPD환자（ A조）、20례중중도COPD환자（ B조）、20례경도중첩종합정환자（ C조）급20례중중도중첩종합정환자（ D조），병근거RDW삼고범위장소유환자분위RDW정상조59례화RDW증고조21례。비교A、 B、 C、 D 4조환자일반자료、동맥혈기분석지표〔pH치、동맥혈양분압（ PaO2）、동맥혈이양화탄분압（ PaCO2）〕、혈장초민C반응단백（ hs－CRP）수평급RDW；비교RDW정상조여RDW증고조환자일반자료、동맥혈기분석지표급혈장hs－CRP수평；병분석RDW여PaO2、혈장hs－CRP수평적상관성。결과4조환자성별、년령급pH치비교，차이무통계학의의（P＞0.05）； A조화B조환자PaO2고우D조，혈장hs－CRP수평화RDW저우D조， C조환자PaCO2저우D조， A조화B조환자RDW저우C조（P＜0.05）。 RDW정상조여RDW증고조환자성별、년령、 pH치급PaCO2비교，차이무통계학의의（ P＞0.05）； RDW증고조환자혈장hs－CRP수평고우RDW정상조、 PaO2저우RDW정상조（P＜0.05）。 Pearson상관분석결과현시， RDW여PaO2정부상관（r＝－0.265， P＝0.018），여혈장hs－CRP수평정정상관（r＝0.258， P＝0.021）。결론 RDW가용우중첩종합정환자염증급기도병변엄중정도적초보평고，구유일정적예측개치。
Objective To investigate the predictive value of red cell distribution width ( RDW) in patients with COPD-OSAHS overlap syndrome.Methods From June 2013 to January 2015 in the Second Clinical College of Ji′nan University, 20 inpatients with mild COPD were selected as A group, 20 inpatients with moderate and severe COPD were selected as B group, 20 inpatients with mild COPD-OSAHS overlap syndrome were selected as C group, 20 inpatients with moderate and severe COPD-OSAHS were selected as D group, and they were also divided into E group (with normal RDW, n=59) and F group ( with increased RDW, n =21 ) according to RDW reference range.General information, arterial blood -gas analysis index ( including pH, PaO2 , PaCO2 ) , plasma hs-CRP level and RDW were compared among the four groups ( A, B, C and D); general information, arterial blood-gas analysis index ( including pH, PaO2 , PaCO2 ) and plasma hs-CRP level were compared between the two groups ( E and F); correlations between RDW and PaO2 , plasma hs-CRP level was respectively analyzed.Results No statistically significant differences of gender, age or pH was found among the four groups ( P>0.05);PaO2 of A group and B group was statistically significantly higher than that of D group, respectively, plasma hs-CRP level of A group and B group was statistically significantly lower than that of D group, respectively, PaCO2 of C group was statistically significantly lower than that of D group, RDW of A group and B group was statistically significantly higher than that of C group, respectively (P<0.05).No statistically significant differences of gender, age, pH or PaCO2 was found between the two groups ( P>0.05); plasma hs-CRP level of F group was statistically significantly higher than that of E group, while PaO2 of F group was statistically significantly lower than that of E group ( P <0.05 ) . Pearson correlation analysis showed that, RDW was negatively correlated with PaO2 (r=-0.265, P=0.018), was positively correlated with plasma hs-CRP level (r=0.258, P=0.021) .Conclusion RDW can be used in the preliminary evaluation of inflammation and airway disease severity in patients with COPD-OSAHS overlap syndrome, has certain predictive value.
