中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
9期
1232-1234,1235
,共4页
药品不良反应%分析%合理用药
藥品不良反應%分析%閤理用藥
약품불량반응%분석%합리용약
Adverse drug reaction%Analysis%Rational drug use
目的：了解安康市中心医院（以下简称“我院”）药品不良反应（ adverse drug reaction ，ADR）的发生情况，为临床合理用药提供参考。方法：采用回顾性分析方法，对2012—2015年我院收集的190例ADR报告中患者性别、年龄及使用药品种类、给药途径等方面进行统计分析。结果：190例ADR中，男性116例，女性74例，男女之比为1.6∶1.0；＞60岁患者46例（占24.21％）；静脉给药引发ADR 127例（占66.84％），口服给药引发ADR 40例（占26.32％）；抗感染药引发ADR 62例次（占合计195例次的31.79％），居首位；ADR的临床表现主要为皮肤及其附件损害（85例次，占合计255例次的33.33％）。结论：应加强医院ADR监测工作，合理、规范用药，避免或减少ADR发生，保证用药安全。
目的：瞭解安康市中心醫院（以下簡稱“我院”）藥品不良反應（ adverse drug reaction ，ADR）的髮生情況，為臨床閤理用藥提供參攷。方法：採用迴顧性分析方法，對2012—2015年我院收集的190例ADR報告中患者性彆、年齡及使用藥品種類、給藥途徑等方麵進行統計分析。結果：190例ADR中，男性116例，女性74例，男女之比為1.6∶1.0；＞60歲患者46例（佔24.21％）；靜脈給藥引髮ADR 127例（佔66.84％），口服給藥引髮ADR 40例（佔26.32％）；抗感染藥引髮ADR 62例次（佔閤計195例次的31.79％），居首位；ADR的臨床錶現主要為皮膚及其附件損害（85例次，佔閤計255例次的33.33％）。結論：應加彊醫院ADR鑑測工作，閤理、規範用藥，避免或減少ADR髮生，保證用藥安全。
목적：료해안강시중심의원（이하간칭“아원”）약품불량반응（ adverse drug reaction ，ADR）적발생정황，위림상합리용약제공삼고。방법：채용회고성분석방법，대2012—2015년아원수집적190례ADR보고중환자성별、년령급사용약품충류、급약도경등방면진행통계분석。결과：190례ADR중，남성116례，녀성74례，남녀지비위1.6∶1.0；＞60세환자46례（점24.21％）；정맥급약인발ADR 127례（점66.84％），구복급약인발ADR 40례（점26.32％）；항감염약인발ADR 62례차（점합계195례차적31.79％），거수위；ADR적림상표현주요위피부급기부건손해（85례차，점합계255례차적33.33％）。결론：응가강의원ADR감측공작，합리、규범용약，피면혹감소ADR발생，보증용약안전。
OBJECTIVE:To investigate the incidence of adverse drug reaction ( ADR) in Ankang Central Hospital ( hereinafter referred to as “our hospital”) , and to provide reference for the promotion of clinical rational use of drug . METHODS:Retrospective analysis was adopted , 190 cases of ADR that collected in our hospital during 2012-2015 were analyzed statistically in terms of patients'gender and age , drug types and route of administration etc .RESULTS:Of the 190 ADR cases, males were 116 cases and females were 74 cases, the male/female ratio was 1.6∶1.0;46 cases(24.21%)aged >60 years;127 cases(66.84%)were induced by intravenous injection;40 cases(26.32%) were induced by oral drugs;62 cases ( 31.79% of the total 195 cases ) were induced by the anti-infectious agents , which dominated the first place of ADR incidence; the clinical manifestation of ADR manifested as skin and its accessories damage (85 cases, 33.33% of the total 255 cases).CONCLUSIONS: It is important to strengthen ADR monitoring, promote the rational and standard drug use in our hospital , so as to avoid or reduce the incidence of ADR to ensure safety in drug use .
