吉林中医药
吉林中醫藥
길림중의약
Jilin Journal of Traditional Chinese Medicine
2015年
9期
910-913
,共4页
小儿%非感染性腹泻%双歧杆菌四联活菌片%苍苓止泻口服液
小兒%非感染性腹瀉%雙歧桿菌四聯活菌片%蒼苓止瀉口服液
소인%비감염성복사%쌍기간균사련활균편%창령지사구복액
children%non infectious diarrhea%Bifidobacterium Tetravaccine tablets%Cangling oral liquid
目的：探讨苍苓止泻口服液联合双歧杆菌四联活菌片治疗小儿非感染性腹泻的临床效果。方法选取130例非感染性腹泻患儿，随机分为观察组和对照组。对照组采用常规方法治疗，观察组在对照组基础上采用苍苓止泻口服液联合双歧杆菌四联活菌片进行治疗，比较2组的总有效率、腹泻停止时间、脱水纠正时间、住院时间及血清IL－6、IL－7及粪便SIgA水平。结果观察组总有效率为96.92％，高于对照组的86.15％，差异有统计学意义（ P＜0.05）；观察组患儿腹泻停止时间、脱水纠正时间及住院时间均较对照组短，差异有统计学意义（ P＜0.05）；治疗72 h ，观察组IL－6和IL－7水平明显较对照组低，差异有统计学意义（ P＜0.05）；治疗组粪便中SIgA水平高于对照组，差异有统计学意义（ P＜0.05）。结论双歧杆菌四联活菌片联合苍苓止泻口服液能有效缩短非感染性腹泻患儿腹泻时间、脱水恢复时间和住院时间，降低IL－6和IL－17水平，增加肠道SIgA水平，减轻患儿体内炎症反应，防御病原体侵入，从而治疗小儿非感染性腹泻。
目的：探討蒼苓止瀉口服液聯閤雙歧桿菌四聯活菌片治療小兒非感染性腹瀉的臨床效果。方法選取130例非感染性腹瀉患兒，隨機分為觀察組和對照組。對照組採用常規方法治療，觀察組在對照組基礎上採用蒼苓止瀉口服液聯閤雙歧桿菌四聯活菌片進行治療，比較2組的總有效率、腹瀉停止時間、脫水糾正時間、住院時間及血清IL－6、IL－7及糞便SIgA水平。結果觀察組總有效率為96.92％，高于對照組的86.15％，差異有統計學意義（ P＜0.05）；觀察組患兒腹瀉停止時間、脫水糾正時間及住院時間均較對照組短，差異有統計學意義（ P＜0.05）；治療72 h ，觀察組IL－6和IL－7水平明顯較對照組低，差異有統計學意義（ P＜0.05）；治療組糞便中SIgA水平高于對照組，差異有統計學意義（ P＜0.05）。結論雙歧桿菌四聯活菌片聯閤蒼苓止瀉口服液能有效縮短非感染性腹瀉患兒腹瀉時間、脫水恢複時間和住院時間，降低IL－6和IL－17水平，增加腸道SIgA水平，減輕患兒體內炎癥反應，防禦病原體侵入，從而治療小兒非感染性腹瀉。
목적：탐토창령지사구복액연합쌍기간균사련활균편치료소인비감염성복사적림상효과。방법선취130례비감염성복사환인，수궤분위관찰조화대조조。대조조채용상규방법치료，관찰조재대조조기출상채용창령지사구복액연합쌍기간균사련활균편진행치료，비교2조적총유효솔、복사정지시간、탈수규정시간、주원시간급혈청IL－6、IL－7급분편SIgA수평。결과관찰조총유효솔위96.92％，고우대조조적86.15％，차이유통계학의의（ P＜0.05）；관찰조환인복사정지시간、탈수규정시간급주원시간균교대조조단，차이유통계학의의（ P＜0.05）；치료72 h ，관찰조IL－6화IL－7수평명현교대조조저，차이유통계학의의（ P＜0.05）；치료조분편중SIgA수평고우대조조，차이유통계학의의（ P＜0.05）。결론쌍기간균사련활균편연합창령지사구복액능유효축단비감염성복사환인복사시간、탈수회복시간화주원시간，강저IL－6화IL－17수평，증가장도SIgA수평，감경환인체내염증반응，방어병원체침입，종이치료소인비감염성복사。
Objective To investigate the Cangling antidiarrheal oral liquid combined with bifid Bacillus tetragenus lacto-bacillus tablets in the treatment of children with non infectious diarrhea clinical effect .Methods Selected 130 cases of non infectious diarrhea were randomly divided into observation group and control group .Control group was treated with conven-tional therapy ,the observation group in the control group on the basis of the Cangling antidiarrheal oral liquid combined with bifid Bacillus tetragenus live bacteria tablets in the treatment of and compared between the two groups the total efficiency , diarrhea stopping time ,dehydration ,correct time ,hospitalization time and serum IL-6 ,IL-7 ,fecal SIgA level .Results The total effective rate in the observation group was 96 .92% ,higher than that of the control group of 86 .15% ,the difference is statistically significant ( P<0 .05 );observation group of children with diarrhea stops time ,dehydration ,correct time and hospitalization time were lower than those in the control group ,the difference is statistically significant ( P<0 .05 );72 hours treatment ,the observation group ,IL-6 and IL-7 levels significantly lower than that in control group ,the difference is statisti-cally significant ( P<0 .05 );treatment group fecal SIgA levels higher than that of the control group ,the difference is statisti-cally significant ( P<0 .05 ) .Conclusion Bifidobacterium quadruple live bacteria tablets combined Cang Ling antidiarrhea oral liquid can effectively shorten the non infectious diarrhea in children with diarrhea time ,dehydration recovery time and hospitalization time ,reduce IL-6 and IL-17 levels ,increased intestinal SIgA level ,reduce the inflammatory response in chil-dren ,and defense against pathogen invasion ,and treatment of children with non infectious diarrhea .
