中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
9期
1145-1146,1147
,共3页
地奥司明片%马应龙麝香痔疮膏%肛肠疾病%术后%疼痛%水肿
地奧司明片%馬應龍麝香痔瘡膏%肛腸疾病%術後%疼痛%水腫
지오사명편%마응룡사향치창고%항장질병%술후%동통%수종
Diosmin tablets%Musk hemorrhoids ointment%Anorectal disease%After surgery%Pain%Edema
目的：探讨地奥司明片与马应龙麝香痔疮膏联合治疗对肛肠疾病术后的影响。方法：选取大连大学附属新华医院肛肠科2013年7月—2014年12月收治的93例肛肠手术患者，以随机数字表法分为观察组47例与对照组46例。对照组患者术后给予地奥司明片，观察组患者在对照组患者基础上加用马应龙麝香痔疮膏，比较2组患者术后疼痛、水肿及不良反应发生情况。结果：观察组患者术后4、7 d的疼痛VAS评分均明显低于对照组[（2.0±0.5）分相比（2.6±0.7）分、（1.1±0.3）分相比（1.5±0.4）分]，差异均有统计学意义（P＜0.05）；观察组患者术后4、7 d的水肿评分及水肿消退时间均明显优于对照组[（1.8±0.4）分相比（2.1±0.6）分、（0.7±0.3）分相比（1.2±0.5）分、（5.2±0.6）d相比（6.4±0.8）d]，差异均有统计学意义（P＜0.05）；2组患者不良反应发生率的差异无统计学意义（ P＞0.05）。结论：肛肠疾病患者术后应用地奥司明片与马应龙麝香痔疮膏联合治疗，可有效发挥活血化瘀、抗菌消炎作用，疼痛与水肿症状得到缓解，值得临床推广。
目的：探討地奧司明片與馬應龍麝香痔瘡膏聯閤治療對肛腸疾病術後的影響。方法：選取大連大學附屬新華醫院肛腸科2013年7月—2014年12月收治的93例肛腸手術患者，以隨機數字錶法分為觀察組47例與對照組46例。對照組患者術後給予地奧司明片，觀察組患者在對照組患者基礎上加用馬應龍麝香痔瘡膏，比較2組患者術後疼痛、水腫及不良反應髮生情況。結果：觀察組患者術後4、7 d的疼痛VAS評分均明顯低于對照組[（2.0±0.5）分相比（2.6±0.7）分、（1.1±0.3）分相比（1.5±0.4）分]，差異均有統計學意義（P＜0.05）；觀察組患者術後4、7 d的水腫評分及水腫消退時間均明顯優于對照組[（1.8±0.4）分相比（2.1±0.6）分、（0.7±0.3）分相比（1.2±0.5）分、（5.2±0.6）d相比（6.4±0.8）d]，差異均有統計學意義（P＜0.05）；2組患者不良反應髮生率的差異無統計學意義（ P＞0.05）。結論：肛腸疾病患者術後應用地奧司明片與馬應龍麝香痔瘡膏聯閤治療，可有效髮揮活血化瘀、抗菌消炎作用，疼痛與水腫癥狀得到緩解，值得臨床推廣。
목적：탐토지오사명편여마응룡사향치창고연합치료대항장질병술후적영향。방법：선취대련대학부속신화의원항장과2013년7월—2014년12월수치적93례항장수술환자，이수궤수자표법분위관찰조47례여대조조46례。대조조환자술후급여지오사명편，관찰조환자재대조조환자기출상가용마응룡사향치창고，비교2조환자술후동통、수종급불량반응발생정황。결과：관찰조환자술후4、7 d적동통VAS평분균명현저우대조조[（2.0±0.5）분상비（2.6±0.7）분、（1.1±0.3）분상비（1.5±0.4）분]，차이균유통계학의의（P＜0.05）；관찰조환자술후4、7 d적수종평분급수종소퇴시간균명현우우대조조[（1.8±0.4）분상비（2.1±0.6）분、（0.7±0.3）분상비（1.2±0.5）분、（5.2±0.6）d상비（6.4±0.8）d]，차이균유통계학의의（P＜0.05）；2조환자불량반응발생솔적차이무통계학의의（ P＞0.05）。결론：항장질병환자술후응용지오사명편여마응룡사향치창고연합치료，가유효발휘활혈화어、항균소염작용，동통여수종증상득도완해，치득림상추엄。
OBJECTIVE:To probe into the effect of Diosmin tablets combined with long musk hemorrhoid ointment on anorectal diseases after surgery .METHODS: 93 cases of surgical patients admitted to the anorectal section in Xinhua Hospital Affiliated to Dalian University from Jul .2013 to Dec.2014 were selected to be randomly divided into the observation group(47 cases)and the control group(46 cases).The control group received Diosmin tablets after surgery , the treatment group additionally received musk hemorrhoids ointment based on the control group .The status of pain, extinction time of edema and occurrence rate of adverse reactions were compared between two groups after surgery .RESULUS:The pain VAS scores of 4 d and 7 d in observation group after surgery were lower than those in the control group [ (2.0 ±0.5) scores vs.(2.6 ±0.7) scores,(1.1 ±0.3) scores vs.(1.5 ±0.4) scores], with statistically significant difference (P<0.05).The edema scores of 4 d and 7 d and extinction time of edema in observation group were significantly better than those in the control group [(1.8 ±0.4) scores vs.(2.1 ±0.6) scores, (0.7 ±0.3) scores vs.(1.2 ±0.5) scores, (5.2 ±0.6) d vs.(6.4 ±0.8) d] , and the differences were statistically significant (P<0.05).There was no statistically significant difference in the incidence rate of adverse reactions in the observation group and control group ( P>0.05). CONCLUSIONS:The application of Diosmin tablets combined with long musk hemorrhoid ointment in treatment of anorectal diseases after surgery plays an effective role in promoting blood circulation to remove blood stasis and antisepsis and anti-inflammation, and can alleviate the symptoms of edema and pain .It is worthy of clinical promotion .
