中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
9期
1187-1189,1190
,共4页
祛风除湿颗粒%质量标准%薄层色谱法%高效液相色谱法%金丝桃苷
祛風除濕顆粒%質量標準%薄層色譜法%高效液相色譜法%金絲桃苷
거풍제습과립%질량표준%박층색보법%고효액상색보법%금사도감
Qufengchushi granules%Quality standard%TLC%HPLC%Hyperoside
目的：建立祛风除湿颗粒的质量标准。方法：采用薄层色谱法对祛风除湿颗粒中石菖蒲、牛膝、甘草进行薄层鉴别，采用高效液相色谱法测定金丝桃苷的含量。结果：石菖蒲、牛膝、甘草的薄层鉴别斑点清晰，阴性无干扰；金丝桃苷在浓度为0.01～0.20 mg／ml范围内呈良好线性关系，平均回收率为100.95％。结论：本研究中方法简便可行，专属性和重复性良好，可用于祛风除湿颗粒的质量控制。
目的：建立祛風除濕顆粒的質量標準。方法：採用薄層色譜法對祛風除濕顆粒中石菖蒲、牛膝、甘草進行薄層鑒彆，採用高效液相色譜法測定金絲桃苷的含量。結果：石菖蒲、牛膝、甘草的薄層鑒彆斑點清晰，陰性無榦擾；金絲桃苷在濃度為0.01～0.20 mg／ml範圍內呈良好線性關繫，平均迴收率為100.95％。結論：本研究中方法簡便可行，專屬性和重複性良好，可用于祛風除濕顆粒的質量控製。
목적：건립거풍제습과립적질량표준。방법：채용박층색보법대거풍제습과립중석창포、우슬、감초진행박층감별，채용고효액상색보법측정금사도감적함량。결과：석창포、우슬、감초적박층감별반점청석，음성무간우；금사도감재농도위0.01～0.20 mg／ml범위내정량호선성관계，평균회수솔위100.95％。결론：본연구중방법간편가행，전속성화중복성량호，가용우거풍제습과립적질량공제。
OBJECTIVE:To establish the quality standard for Qufengchushi granules .METHODS: TLC method was adopted to identify Acorus tatarinowii, Achyranthes bidentata blume and Glycyrrhiza uralensis fisch in Qufengchushi granules.And the content of hyperoside was identified by HPLC method .RESULTS: The spots of TLC of A. tatarinowii, A.bidentata blume and G.uralensis fisch were fairly clear, and the blank test showed no interference .For hyperoside , the linearity was good within the range of 0.01-0.20 mg/ml and the average recovery was 100.95%. CONCLUSIONS:The method is simple , reliable and reproducible , which can be applied as a quantity control method of Qufengchushi granules .
