CAJ | 학술논문

目的：观察采用阿奇霉素、头孢哌酮／舒巴坦联合小剂量地塞米松治疗大《性肺炎的效果。方法选择大《性肺炎患者172例，按照随机数字表法分为对照组和观察组各86例。对照组给予阿奇霉素联合小剂量地塞米松治疗，观察组给予阿奇霉素、头孢哌酮／舒巴坦联合小剂量地塞米松治疗，比较两组患者的临床疗效和不良反应的发生率。结果观察组疗效明显优于对照组（95.35％vs 86.05％，P＜0.05）。治疗过程中，过敏性皮疹、过敏性休克、寒颤、呼吸急促等不良反应发生率对照组为9.30％，观察组为16.28％，两组比较差异无统计学意义（ P＞0.05）。结论采用阿奇霉素、头孢哌酮／舒巴坦联合小剂量地塞米松治疗大《性肺炎患者临床效果较为显著，不良反应少，值得临床推广使用。
목적：관찰채용아기매소、두포고동／서파탄연합소제량지새미송치료대《성폐염적효과。방법선택대《성폐염환자172례，안조수궤수자표법분위대조조화관찰조각86례。대조조급여아기매소연합소제량지새미송치료，관찰조급여아기매소、두포고동／서파탄연합소제량지새미송치료，비교량조환자적림상료효화불량반응적발생솔。결과관찰조료효명현우우대조조（95.35％vs 86.05％，P＜0.05）。치료과정중，과민성피진、과민성휴극、한전、호흡급촉등불량반응발생솔대조조위9.30％，관찰조위16.28％，량조비교차이무통계학의의（ P＞0.05）。결론채용아기매소、두포고동／서파탄연합소제량지새미송치료대《성폐염환자림상효과교위현저，불량반응소，치득림상추엄사용。
Objective To explore the effect of the joint use of azithromycin , cefoperazone/sulbactam and dexamethasone on patients with lobar pneumonia .Methods 172 patients with lobar pneumonia were collected and divided into the control group and the observation group by the random number table method , with 86 cases in each group.The patients of the control group were given azithromycin combination with a small dose of dexamethasone treatment.The patients of the observation group were given azithromycin , cefoperazone/sulbactam in combination with a small dose of dexamethasone treatment .The clinical curative effects and adverse reactions were compared be-tween the two groups .Results The total effective rate was elevated in the observation group than that in the control group(95.35 %vs 86.05%, P<0.05).The incidence of adverse reactions such as allergic skin rashes , anaphylac-tic shock, chills and shortness of breath was 9.30%in the observation group , and 16.28%in the control group , with no significant difference ( P>0.05 ) .Conclusion The combination use of azithromycin , cefoperazone/sulbactam and a small dose of dexamethasone in the treatment of lobar pneumonia is effective and safe .