CAJ | 학술논문

目的：探讨糖皮质激素阻止和治疗新生儿慢性肺损伤中的临床治疗效果。方法：选取吉林油田总医院的120例慢性肺损伤早产儿，按随机数字表法分为观察组和对照组各60例，对照组患儿行持续通过机械通气氧气支持治疗，观察组患儿采用糖皮质激素治疗，比较2组的临床疗效、并发症等情况。结果：对照组患儿总有效率为25.00％（15／60），观察组患儿的总有效率为43.33％（26／60），差异有统计学意义（P＜0.05）；2组患儿脑出血发生率、脑室周围软化发生率、病死率的差异无统计学意义（P＞0.05）。结论：糖皮质激素对新生儿慢性肺损伤的阻止及治疗效果较好，能缓解患儿的病情，促进患儿预后。
목적：탐토당피질격소조지화치료신생인만성폐손상중적림상치료효과。방법：선취길림유전총의원적120례만성폐손상조산인，안수궤수자표법분위관찰조화대조조각60례，대조조환인행지속통과궤계통기양기지지치료，관찰조환인채용당피질격소치료，비교2조적림상료효、병발증등정황。결과：대조조환인총유효솔위25.00％（15／60），관찰조환인적총유효솔위43.33％（26／60），차이유통계학의의（P＜0.05）；2조환인뇌출혈발생솔、뇌실주위연화발생솔、병사솔적차이무통계학의의（P＞0.05）。결론：당피질격소대신생인만성폐손상적조지급치료효과교호，능완해환인적병정，촉진환인예후。
OBJECTIVE:To study the clinic efficacy of application of glucocorticoid in prevention and treatment of neonatal chronic lung injury .METHODS: 120 cases of patients with chronic lung injury in Jilin Oil Field General Hospitalwere selected to be divided into observation group and control group via random number table , with 60 cases in each group .The control group received mechanical ventilation oxygen therapy , the observation group were treated with glucocorticoid , the clinical efficacy and complication were analyzed and compared in two groups .RESULTS:The total effective rate was 25.00%(15/60)in control group,and 43.33%(26/60)in observation group, there were statistically significant differences between two groups (P<0.05).There was no significant difference in the incidence of cerebral hemorrhage , the incidence of periventircular encephalomalacia and the mortality in the 2 groups ( P >0.05 ) . CONCLUSIONS:The clinic efficacy of application of glucocorticoid in prevention and treatment of neonatal chronic lung injury is effective , which can relief the pathogenetic conditions of the children and promote the prognosis .