CAJ | 학술논문

目的：探讨儿童无症状血尿的病因和转归?方法回顾性分析2001年1月至2014年12月就诊的431例无症状血尿患儿的病因、临床特点及预后?结果431例患儿中，男197例、女234例，初诊年龄（5.52±2.77）岁（8个月~17岁）；持续镜下血尿425例，发作性肉眼血尿6例。肾小球源性血尿315例（73.1%），其中临床诊断为孤立性血尿286例，急性肾小球肾炎5例；病理诊断肾小球轻微病变13例，IgA肾病4例，系膜增生性肾小球肾炎4例，薄基底膜肾病3例。非肾小球源性血尿136例（31.5%），其中左肾静脉压迫综合征113例，特发性高钙尿症17例，肾结石4例，泌尿道感染1例，左肾缺如1例。286例孤立性血尿患儿随访（3.05±2.69）年（0.5~13.5年），145例（50.7%）血尿消失，其中110例在初诊后3年内消失；24例伴有血尿家族史的患儿中仅有6例血尿消失；所有孤立性血尿患儿随访结束时肾功能都维持良好?结论儿童无症状血尿发病年龄跨度大，以肾小球源性血尿居多；儿童孤立性血尿大多在初诊后3年内消失，伴有血尿家族史者血尿持续时间可能更长；儿童期孤立性血尿预后良好，需长期随访。
목적：탐토인동무증상혈뇨적병인화전귀?방법회고성분석2001년1월지2014년12월취진적431례무증상혈뇨환인적병인、림상특점급예후?결과431례환인중，남197례、녀234례，초진년령（5.52±2.77）세（8개월~17세）；지속경하혈뇨425례，발작성육안혈뇨6례。신소구원성혈뇨315례（73.1%），기중림상진단위고립성혈뇨286례，급성신소구신염5례；병리진단신소구경미병변13례，IgA신병4례，계막증생성신소구신염4례，박기저막신병3례。비신소구원성혈뇨136례（31.5%），기중좌신정맥압박종합정113례，특발성고개뇨증17례，신결석4례，비뇨도감염1례，좌신결여1례。286례고립성혈뇨환인수방（3.05±2.69）년（0.5~13.5년），145례（50.7%）혈뇨소실，기중110례재초진후3년내소실；24례반유혈뇨가족사적환인중부유6례혈뇨소실；소유고립성혈뇨환인수방결속시신공능도유지량호?결론인동무증상혈뇨발병년령과도대，이신소구원성혈뇨거다；인동고립성혈뇨대다재초진후3년내소실，반유혈뇨가족사자혈뇨지속시간가능경장；인동기고립성혈뇨예후량호，수장기수방。
ObjectiveTo investigate the etiology and prognosis of asymptomatic hematuria in children.MethodsThe etiological factors, clinical features and prognosis of asymptomatic hematuria were analyzed retrospectively in 431 children from Jan. 2001 to Dec . 2014. ResultsIn 431 children (197 males and 234 females) with asymptomatic hematuria, the mean age of ifrst visit was 5.52±2.77 years (8 months-17 years). Four hundred and twenty-ifve cases had persistent microscopic hematuria and 6 cases had gross hematuria. Three hundred and iffteen cases (73.1%) were glomerular hematuria, among which 286 cases were isolated hematuria, 5 cases were acute glomerulonephritis, 13 cases were minimal change glomerulopathy, 4 cases were IgA nephropathy, 4 cases were mesangial proliferation glomerulonephritis and 3 cases were thin basement membrane nephropathy. One hundred and thirty-six cases (31.5%) were non-glomerular hematuria, among whom 113 cases were left renal vein entrap-ment syndrome, 17 cases were idiopathic hypercalciuria, 4 cases were kidney stone, 1 case was urinary tract infection and 1 case was left kidney absence. The mean follow-up period was 3.05±2.69 years (0.5-13.5 years). One hundred and forty-ifve patients showed the resolution of microscopic hematuria, among whom 110 cases (75.8%) had the resolution in 3 years after the ifrst visit. In 24 cases with family history of hematuria, only 6 cases showed the resolution. At the end of the follow-up, renal function remained stable in all children.ConclusionsThe onset age of asymptomatic hematuria in children varies widely, and most of them are glomerular hematuria. Most children with isolated hematuria show resolution within three years after the ifrst visit. The children with familial hematuria may last longer. The isolated hematuria has good prognosis but needs to be followed up.