中国医院用药评价与分析
中國醫院用藥評價與分析
중국의원용약평개여분석
Evaluation and Analysis of Drug-Use in Hospitals of China
2015年
9期
1158-1159
,共2页
七氟醚%丙泊酚%复合麻醉%术后认知功能
七氟醚%丙泊酚%複閤痳醉%術後認知功能
칠불미%병박분%복합마취%술후인지공능
Sevoflurane%Propofol%Combined anesthesia%Postoperative cognitive function
目的：观察七氟醚复合丙泊酚静脉麻醉对老年患者术后认知功能的影响。方法：选取120例老年手术患者，以随机数字表法分为对照组和观察组各60例。对照组患者给予靶控静脉注射模式麻醉，观察组患者在对照组基础上给予七氟醚复合丙泊酚静脉麻醉，对比观察2组患者术后清醒时间及认知功能评估结果。结果：观察组患者平均术后清醒时间为（20.51±1.55） min，对照组患者为（20.12±1.95） min，差异无统计学意义（P＞0.05）；观察组患者术后认知功能障碍发生率为11.67％（7／60），明显低于对照组患者的21.67％（13／60），差异有统计学意义（P＜0.05）。结论：七氟醚复合丙泊酚静脉麻醉对老年患者术后认知功能具有显著的改善效果，且不会影响患者术后清醒时间，值得临床推广。
目的：觀察七氟醚複閤丙泊酚靜脈痳醉對老年患者術後認知功能的影響。方法：選取120例老年手術患者，以隨機數字錶法分為對照組和觀察組各60例。對照組患者給予靶控靜脈註射模式痳醉，觀察組患者在對照組基礎上給予七氟醚複閤丙泊酚靜脈痳醉，對比觀察2組患者術後清醒時間及認知功能評估結果。結果：觀察組患者平均術後清醒時間為（20.51±1.55） min，對照組患者為（20.12±1.95） min，差異無統計學意義（P＞0.05）；觀察組患者術後認知功能障礙髮生率為11.67％（7／60），明顯低于對照組患者的21.67％（13／60），差異有統計學意義（P＜0.05）。結論：七氟醚複閤丙泊酚靜脈痳醉對老年患者術後認知功能具有顯著的改善效果，且不會影響患者術後清醒時間，值得臨床推廣。
목적：관찰칠불미복합병박분정맥마취대노년환자술후인지공능적영향。방법：선취120례노년수술환자，이수궤수자표법분위대조조화관찰조각60례。대조조환자급여파공정맥주사모식마취，관찰조환자재대조조기출상급여칠불미복합병박분정맥마취，대비관찰2조환자술후청성시간급인지공능평고결과。결과：관찰조환자평균술후청성시간위（20.51±1.55） min，대조조환자위（20.12±1.95） min，차이무통계학의의（P＞0.05）；관찰조환자술후인지공능장애발생솔위11.67％（7／60），명현저우대조조환자적21.67％（13／60），차이유통계학의의（P＜0.05）。결론：칠불미복합병박분정맥마취대노년환자술후인지공능구유현저적개선효과，차불회영향환자술후청성시간，치득림상추엄。
OBJECTIVE:To observe the effect of sevoflurane combined with propofol intravenous anesthesia on postoperative cognitive function in elderly patients .METHODS: 120 cases of elderly patients were selected to be divided into control group and observation group via random number table , with 60 cases in each group .The control group received target controlled intravenous ( TCI ) model combined with intravenous anesthesia; based on the control group, the observation group additionally received sevoflurane combined with propofol intravenous anesthesia .The postoperative recovery time and cognitive function in two groups were observed and compared .RESULTS:The average postoperative recovery time was (20.51 ±1.55) min in observation group, and (20.12 ±1.95) min in control group, with no statistically significant difference ( P>0.05 ) .The incidence of cognitive dysfunction was 11.67%( 7/60 ) in observation group , which was lower than that in control group [ 21.67%( 13/60 ) ] , with statistically significant difference(P<0.05).CONCLUSIONS:Sevoflurane combined with propofol intravenous anesthesia have a significant improvement effect on the postoperative cognitive function in elderly patients , and would not affect the recovery time of patients;it is worthy of clinical promotion .
