中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
Chinese Journal of Woman and Child Health Research
2015年
4期
780-782
,共3页
慢性盆腔炎%金刚藤%妇科千金片%白介素-6%粒-巨核细胞集落刺激因子
慢性盆腔炎%金剛籐%婦科韆金片%白介素-6%粒-巨覈細胞集落刺激因子
만성분강염%금강등%부과천금편%백개소-6%립-거핵세포집락자격인자
chronic pelvic inflammation%Jingangteng%Qianjinpian%interleukin-6 ( IL-6 )%grain-megakaryocyte colony stimulating factor ( GM-CSF)
目的 探讨金刚藤联合妇科千金片对慢性盆腔炎的疗效及其对患者血清白介素-6(IL-6)和粒-巨核细胞集落刺激因子(GM-CSF)水平的影响. 方法 将73例慢性盆腔炎患者按照随机分组方法分为对照组(n=35)与观察组(n=38). 对照组仅采用妇科千金片进行治疗,观察组在此基础上联合金刚藤进行治疗. 比较两组的临床疗效、体温恢复时间、腹痛消失时间、住院时间、治疗后生活质量、治疗前后血清IL-6 和GM-CSF水平变化情况及不良反应发生率. 结果 对照组临床总有效率为74.29%,显著低于观察组(92.11%)(χ2 =5.672,P<0.05);观察组体温恢复时间、腹痛消失时间、住院时间均显著小于对照组(t值分别为5.193、7.021、11.021,均P<0.05);根据SF-36生活质量评分量表,观察组治疗后量表各维度评分均显著高于对照组(t=3.453~6.764,均P<0.05);两组治疗后血清IL-6和GM-CSF水平均显著低于治疗前(t值分别为13.458、2.342,14.234、2.565,均P<0.05),且观察组治疗后上述指标水平均显著低于对照组治疗后(t值分别为10.234、3.425,均P<0.05);对照组治疗后不良反应发生率为17.14%,显著高于观察组(10.53%)(χ2 =4.998,P<0.05). 结论 金刚藤联合妇科千金片对慢性盆腔炎的疗效显著,可显著降低血清IL-6及GM-CSF水平,可在临床上进行推广.
目的 探討金剛籐聯閤婦科韆金片對慢性盆腔炎的療效及其對患者血清白介素-6(IL-6)和粒-巨覈細胞集落刺激因子(GM-CSF)水平的影響. 方法 將73例慢性盆腔炎患者按照隨機分組方法分為對照組(n=35)與觀察組(n=38). 對照組僅採用婦科韆金片進行治療,觀察組在此基礎上聯閤金剛籐進行治療. 比較兩組的臨床療效、體溫恢複時間、腹痛消失時間、住院時間、治療後生活質量、治療前後血清IL-6 和GM-CSF水平變化情況及不良反應髮生率. 結果 對照組臨床總有效率為74.29%,顯著低于觀察組(92.11%)(χ2 =5.672,P<0.05);觀察組體溫恢複時間、腹痛消失時間、住院時間均顯著小于對照組(t值分彆為5.193、7.021、11.021,均P<0.05);根據SF-36生活質量評分量錶,觀察組治療後量錶各維度評分均顯著高于對照組(t=3.453~6.764,均P<0.05);兩組治療後血清IL-6和GM-CSF水平均顯著低于治療前(t值分彆為13.458、2.342,14.234、2.565,均P<0.05),且觀察組治療後上述指標水平均顯著低于對照組治療後(t值分彆為10.234、3.425,均P<0.05);對照組治療後不良反應髮生率為17.14%,顯著高于觀察組(10.53%)(χ2 =4.998,P<0.05). 結論 金剛籐聯閤婦科韆金片對慢性盆腔炎的療效顯著,可顯著降低血清IL-6及GM-CSF水平,可在臨床上進行推廣.
목적 탐토금강등연합부과천금편대만성분강염적료효급기대환자혈청백개소-6(IL-6)화립-거핵세포집락자격인자(GM-CSF)수평적영향. 방법 장73례만성분강염환자안조수궤분조방법분위대조조(n=35)여관찰조(n=38). 대조조부채용부과천금편진행치료,관찰조재차기출상연합금강등진행치료. 비교량조적림상료효、체온회복시간、복통소실시간、주원시간、치료후생활질량、치료전후혈청IL-6 화GM-CSF수평변화정황급불량반응발생솔. 결과 대조조림상총유효솔위74.29%,현저저우관찰조(92.11%)(χ2 =5.672,P<0.05);관찰조체온회복시간、복통소실시간、주원시간균현저소우대조조(t치분별위5.193、7.021、11.021,균P<0.05);근거SF-36생활질량평분량표,관찰조치료후량표각유도평분균현저고우대조조(t=3.453~6.764,균P<0.05);량조치료후혈청IL-6화GM-CSF수평균현저저우치료전(t치분별위13.458、2.342,14.234、2.565,균P<0.05),차관찰조치료후상술지표수평균현저저우대조조치료후(t치분별위10.234、3.425,균P<0.05);대조조치료후불량반응발생솔위17.14%,현저고우관찰조(10.53%)(χ2 =4.998,P<0.05). 결론 금강등연합부과천금편대만성분강염적료효현저,가현저강저혈청IL-6급GM-CSF수평,가재림상상진행추엄.
Objective To investigate the curative effect of Jingangteng combined with Qianjinpian on chronic pelvic inflammation and its influence on levels of serum cytokines interleukin-6 ( IL-6 ) and grain-megakaryocyte colony stimulating factor ( GM-CSF ) .Methods Totally 73 cases of chronic pelvic inflammation were randomly divided into control group ( n=35 ) and observation group ( n=38 ) .The control group used Qianjinpian treatment only, and the observation group was treated with Jingangteng combining Qianjinpian treatment. Two groups were compared in terms of clinical efficacy, body temperature recovery time, abdominal pain disappearance time, hospital stay, life quality after treatment, serum levels of IL-6 and GM-CSF before and after treatment, and the incidence of adverse reactions.Results The total effective rate of the control group was 74.29%, which was significantly lower than that of the observation group (92.11%) (χ2 =5.672,P<0.05).The temperature recovery time, abdominal pain disappearance time, and length of hospital stay were significantly shorter in the observation group than in the control group (t value was 5.193, 7.021 and 11.021, respectively, all P<0.05).SF-36 life quality rating scale showed that after treatment the scores of each dimension were significantly higher in the observation group ( t value ranged 3.453-6.764,P<0.05).After treatment the serum IL-6 and GM-CSF levels declined in two groups (t value was 13.458, 2.342, 14.234 and 2.565, respectively, all P<0.05), and those in the observation group were significantly lower than those in the control group (t value was 10.234 and 3.425, respectively, both P<0.05).In the control group the occurrence of adverse reactions after treatment was 17.14%, which was significantly higher than that in the observation group (10.53%) (χ2 =4.998,P<0.05).Conclusion Jingangteng combined with Qianjinpian has remarkable efficacy on chronic pelvic inflammation and can significantly reduce serum IL-6 and GM-CSF levels, so it should be promoted in clinical practice.
