CAJ | 학술논문

目的：探讨血清降钙素原（procalcitonin ，PCT ）检测在急诊发热患者诊断中的价值。方法采用电化学发光免疫法测定120例急诊发热患者的血清PCT水平并同时检测白细胞（white blood cell ，WBC）、C反应蛋白（CRP），以细菌培养阳性作为细菌感染诊断的金标准。WBC、CRP、PCT分别以WBC＞10．0×109／L，CRP＞10mg／L，PCT＞0．5μg／L判断为升高。结果73例患者细菌培养检出病原菌，47例未培养出病原细菌；63例患者PCT、WBC、CRP水平同时升高；2例患者WBC升高，PCT、CRP不升高；6例患者PCT升高，WBC、CRP不升高；4例患者PCT、CRP升高，WBC不升高；35例患者 PCT、WBC、CRP同时保持低水平。结论血清PC T水平可作为急诊发热患者细菌感染的辅助诊断指标。
목적：탐토혈청강개소원（procalcitonin ，PCT ）검측재급진발열환자진단중적개치。방법채용전화학발광면역법측정120례급진발열환자적혈청PCT수평병동시검측백세포（white blood cell ，WBC）、C반응단백（CRP），이세균배양양성작위세균감염진단적금표준。WBC、CRP、PCT분별이WBC＞10．0×109／L，CRP＞10mg／L，PCT＞0．5μg／L판단위승고。결과73례환자세균배양검출병원균，47례미배양출병원세균；63례환자PCT、WBC、CRP수평동시승고；2례환자WBC승고，PCT、CRP불승고；6례환자PCT승고，WBC、CRP불승고；4례환자PCT、CRP승고，WBC불승고；35례환자 PCT、WBC、CRP동시보지저수평。결론혈청PC T수평가작위급진발열환자세균감염적보조진단지표。
Objective To evaluate the serum rocalcitonin(PCT) determination in the diagnosis of emergency patients with fever . Methods 120emergencypatientswithfeverwereenrolledinthestudy,whoseserumsamplesweretestedbyusingelectrochemilu‐minescence immunoassay for PCT concentrations ,at the same time white blood cells(WBC) count and C reactive protein(CRP) were also determined .Bacterial culture results were used as gold standard for the diagnosis of bacterial infection .WBC>10 .0 × 109/L,CRP>10mg/L,PCT>0.5μg/Lwerethejudgmentcriteriafortheevaluationofthoseindicators.Results 73casesofpatients′bacteria culture results were positive ,47 patients′bacteria culture results were negative;63 cases of patients were with PCT ,WBC and CRP levels elevated at the same time;2 patients′WBC count elevated ,while PCT and CRP concentrations did not ;6 patients′serum PCT concentrations increased ,while WBC and CRP levels didn′t ;4 patients′serum PCT and CRP concentration increased , while WBC count didn′t ;35 patients′PCT ,WBC and CRP kept at low levels .Conclusion Serum PCT concentration could be used as an auxiliary diagnosis indicator in the diagnosis of emergency patients with fever .