CAJ | 학술논문

为了解达斡尔族与汉族糖尿病患者的临床差异,对967例糖尿病患者的临床资料及血糖、糖化血红蛋白(HbA1c)、血脂、尿酸等实验室指标进行分析.结果显示,967例糖尿病中达斡尔族425例(44.0％),汉族542例(56.0％),达斡尔族糖尿病患者较汉族糖尿病患者平均年龄低(55±11)岁比(58±10)岁,P=0.000,发病年龄早(50±10)岁比(53±11)岁,P=0.000,男性比例高(54.8％比46.9％,P=0.008),农村居民比例多(42.1％比36.2％,P=0.034),空腹血糖低(9.25±3.37) mmol/L比(10.28 ±4.33) mmol/L,P =0.000,HbA1c(7.61±1.71)％比(7.29±1.63)％,P=0.008、TG(2.91±2.06) mmol/L比(2.36 ±2.13) mmol/L,P=0.008、LDL-C(3.22±1.06)mmol/L比(3.01 ±0.92) mmol/L,P=0.020、收缩压(139.48 ±21.58)mmHg(1 mmHg =0.133 kPa)比(136.37±23.44) mmHg,P=0.002、舒张压(87.23±12.59 mmHg)比(85.32±12.52) mmHg,P=0.0I9、血尿酸(324.97±106.45) μmol/L比(285.32±98.69) μmol/L,P=0.000、尿微量白蛋白/尿肌酐比值(2.29±5.57) mg/g比(0.12±0.98) mg/g,P=0.000均高,差异均有统计学意义.提示,与当地常驻汉族比较,达斡尔族糖尿病患者患病年龄早,HbA1c、血压、尿酸、血脂等异常更重,糖尿病导致的肾脏损害或心血管疾病可能性增加,应根据患者的特点进行糖尿病防控.
위료해체알이족여한족당뇨병환자적림상차이,대967례당뇨병환자적림상자료급혈당、당화혈홍단백(HbA1c)、혈지、뇨산등실험실지표진행분석.결과현시,967례당뇨병중체알이족425례(44.0％),한족542례(56.0％),체알이족당뇨병환자교한족당뇨병환자평균년령저(55±11)세비(58±10)세,P=0.000,발병년령조(50±10)세비(53±11)세,P=0.000,남성비례고(54.8％비46.9％,P=0.008),농촌거민비례다(42.1％비36.2％,P=0.034),공복혈당저(9.25±3.37) mmol/L비(10.28 ±4.33) mmol/L,P =0.000,HbA1c(7.61±1.71)％비(7.29±1.63)％,P=0.008、TG(2.91±2.06) mmol/L비(2.36 ±2.13) mmol/L,P=0.008、LDL-C(3.22±1.06)mmol/L비(3.01 ±0.92) mmol/L,P=0.020、수축압(139.48 ±21.58)mmHg(1 mmHg =0.133 kPa)비(136.37±23.44) mmHg,P=0.002、서장압(87.23±12.59 mmHg)비(85.32±12.52) mmHg,P=0.0I9、혈뇨산(324.97±106.45) μmol/L비(285.32±98.69) μmol/L,P=0.000、뇨미량백단백/뇨기항비치(2.29±5.57) mg/g비(0.12±0.98) mg/g,P=0.000균고,차이균유통계학의의.제시,여당지상주한족비교,체알이족당뇨병환자환병년령조,HbA1c、혈압、뇨산、혈지등이상경중,당뇨병도치적신장손해혹심혈관질병가능성증가,응근거환자적특점진행당뇨병방공.
Total 967 patients with diabetes mellitus treated in Morindawa People's Hospital from June 2012 to June 2014 were included in the study,among them 425 (44.0％) were of Daur nationality and 542 (56.0％) were of Han nationality.The clinical data and laboratory tests were analyzed and compared between two groups.Compared with Han nationality,Daur patients presented a younger average age[(55 ± 1 1) y vs.(58 ± 1 0) y,P=0.000],an earlier age of onset[(50±10)y vs.(53 ± 1 1) y,P=0.000],a higher percentage of males (54.8％ vs.46.9％,P =0.008),a higher percentage of rural residents (42.1％ vs.36.2％,P =0.034),a lower level of fasting blood-glucose (FBG) [(9.25 ± 3.37) mmol/L vs.(10.28 ±4.33) mmol/L,P =0.000],higher levels of HbA1c [(7.61 ± 1.71)％ vs.(7.29 ± 1.63)％,P=0.008],triglyceride (TG) [(2.91 ±2.06) mmol/L vs.(2.36 ±2.13) mmol/L,P =0.008],low density lipoprotein cholesterol (LDL-C) [(3.22 ± 1.06) mmol/L vs.(3.01 ±0.92)mmol/L,P=0.020],systolic blood pressure (SBP) [(139.48 ± 21.58) mmHg (1 mmHg =0.133 kPa) vs.(136.37 ± 23.44) mmHg,P =0.002],diastolic blood pressure (DBP) [(87.23 ± 12.59) mmHg vs.(85.32 ± 12.52) mmHg,P =0.019],blood uric acid [(324.97 ± 106.45) μmol/L vs.(285.32 ± 98.69) μmol/L,P =0.000] and the ratio of urine microalbumin to urine creatinine [(2.29 ±5.57) mg/g vs.(0.12 ±0.98) mg/g,P =0.000].The results show that Daur diabetic patients are.younger in age,with more severe disorders in HbA1 c,blood pressure,blood uric acid and lipids levels,which increase the probability of renal damage or cardiovascular diseases in these patients.