河南医学研究
河南醫學研究
하남의학연구
Henan Medical Research
2015年
10期
19-20
,共2页
长春西汀%川芎嗪%糖尿病周围神经病变
長春西汀%川芎嗪%糖尿病週圍神經病變
장춘서정%천궁진%당뇨병주위신경병변
vinpocetine%ligustrazine%diabetic peripheral neuropathy
目的：观察长春西汀治疗糖尿病周围神经病变的疗效及安全性。方法选取2009年1月至2014年3月商丘市第一人民医院收治的252例糖尿病周围神经病变患者，随机分为治疗组（130例）和对照组（122例）。治疗组给予长春西汀治疗，对照组给予川芎嗪治疗。观察对比两组患者神经功能、生活能力改善情况及不良反应发生率。结果与对照组比较，治疗组患者神经功能缺损评分明显降低，生活能力评分明显提高（P ＜0．05）。两组治疗过程中均未发生严重不良反应。结论长春西汀治疗糖尿病周围神经病变可有效改善神经功能，安全性较高，值得临床推广。
目的：觀察長春西汀治療糖尿病週圍神經病變的療效及安全性。方法選取2009年1月至2014年3月商丘市第一人民醫院收治的252例糖尿病週圍神經病變患者，隨機分為治療組（130例）和對照組（122例）。治療組給予長春西汀治療，對照組給予川芎嗪治療。觀察對比兩組患者神經功能、生活能力改善情況及不良反應髮生率。結果與對照組比較，治療組患者神經功能缺損評分明顯降低，生活能力評分明顯提高（P ＜0．05）。兩組治療過程中均未髮生嚴重不良反應。結論長春西汀治療糖尿病週圍神經病變可有效改善神經功能，安全性較高，值得臨床推廣。
목적：관찰장춘서정치료당뇨병주위신경병변적료효급안전성。방법선취2009년1월지2014년3월상구시제일인민의원수치적252례당뇨병주위신경병변환자，수궤분위치료조（130례）화대조조（122례）。치료조급여장춘서정치료，대조조급여천궁진치료。관찰대비량조환자신경공능、생활능력개선정황급불량반응발생솔。결과여대조조비교，치료조환자신경공능결손평분명현강저，생활능력평분명현제고（P ＜0．05）。량조치료과정중균미발생엄중불량반응。결론장춘서정치료당뇨병주위신경병변가유효개선신경공능，안전성교고，치득림상추엄。
Objective To analyze the efficacy and safety of vinpocetine in the treatment of diabetic peripheral neuropathy. Methods 252 patients with diabetic peripheral neuropathy treated in The First People's Hospital of Shangqiu City from January of 2009 to March of 2014 were selected and randomly divided into treatment group(130 cases)and control group(122 cases). The treatment group was treated with vinpocetine while the control group was treated with ligustrazine.The nerve function,ability of daily living and adverse reactions were compared.Results The scores of nerve function and ability of daily living were better than control group(P <0.05).There were no adverse reaction found in the treatment.Conclusion Vinpocetine had a good effi-cacy and safety in the treatment of diabetic peripheral neuropathy,deserving the clinical expasion.
