福建医科大学学报
福建醫科大學學報
복건의과대학학보
Journal of Fujian Medical University
2015年
3期
187-190,206
,共5页
妊娠%白血病%妊娠结局%预后
妊娠%白血病%妊娠結跼%預後
임신%백혈병%임신결국%예후
pregnancy%leukemia%pregnancy outcome%prognosis
目的:探讨妊娠合并白血病患者的临床处理及妊娠结局。方法收集27例妊娠合并白血病患者的临床资料,回顾性分析其孕期特点、临床处理及妊娠结局进行分析。结果(1)孕期临床处理及妊娠结局:孕前诊断9例,8例均足月分娩,1例在孕早期流产后继续化疗。孕早期诊断3例:2例流产后化疗,1例足月分娩。孕中期诊断11例:6例足月分娩,1例死亡,4例行引产后化疗。孕晚期诊断的共4例,均足月分娩。(2)母婴随访情况:失访5例,其余随访时间6~144月,母亲12例存活,10例死亡;27例中有19例活产,分娩后胎儿Apgar评分均>7分,随访至今仍健在,未发现胎儿畸形、发育不良、白血病等病史。结论白血病患者在病情缓解后慎重妊娠,可望得到较好的妊娠结局。白血病本身及治疗对于胎儿及孕妇存在一定风险,需要在有条件的综合性医院进行治疗及监管。
目的:探討妊娠閤併白血病患者的臨床處理及妊娠結跼。方法收集27例妊娠閤併白血病患者的臨床資料,迴顧性分析其孕期特點、臨床處理及妊娠結跼進行分析。結果(1)孕期臨床處理及妊娠結跼:孕前診斷9例,8例均足月分娩,1例在孕早期流產後繼續化療。孕早期診斷3例:2例流產後化療,1例足月分娩。孕中期診斷11例:6例足月分娩,1例死亡,4例行引產後化療。孕晚期診斷的共4例,均足月分娩。(2)母嬰隨訪情況:失訪5例,其餘隨訪時間6~144月,母親12例存活,10例死亡;27例中有19例活產,分娩後胎兒Apgar評分均>7分,隨訪至今仍健在,未髮現胎兒畸形、髮育不良、白血病等病史。結論白血病患者在病情緩解後慎重妊娠,可望得到較好的妊娠結跼。白血病本身及治療對于胎兒及孕婦存在一定風險,需要在有條件的綜閤性醫院進行治療及鑑管。
목적:탐토임신합병백혈병환자적림상처리급임신결국。방법수집27례임신합병백혈병환자적림상자료,회고성분석기잉기특점、림상처리급임신결국진행분석。결과(1)잉기림상처리급임신결국:잉전진단9례,8례균족월분면,1례재잉조기유산후계속화료。잉조기진단3례:2례유산후화료,1례족월분면。잉중기진단11례:6례족월분면,1례사망,4례행인산후화료。잉만기진단적공4례,균족월분면。(2)모영수방정황:실방5례,기여수방시간6~144월,모친12례존활,10례사망;27례중유19례활산,분면후태인Apgar평분균>7분,수방지금잉건재,미발현태인기형、발육불량、백혈병등병사。결론백혈병환자재병정완해후신중임신,가망득도교호적임신결국。백혈병본신급치료대우태인급잉부존재일정풍험,수요재유조건적종합성의원진행치료급감관。
Objective To discuss the treatment and prognosis of leukemia complicating pregnan‐cy . Methods The clinical data of 27 cases of leukemia complicating pregnancy were retrospectively ana‐lyzed . Data analyzed included pregnancy features ,clinical treatment ,and pregnancy outcomes . Results (1)The clinical treatment during pregnancy and pregnancy outcome:Of the nine cases diagnosed before pregnancy ,eight were delivered in full‐term and one continued chemotherapy after abortion in the early pregnancy term . Of the three cases diagnosed in the early pregnancy term ,two received chemotherapy after abortion and one was delivered in full‐term . Of the eleven cases diagnosed in the mid term ,six were delivered in full‐term ,four received chemotherapy after induction of labor and one died . Four cases were diagnosed in the late pregnancy term ,all of whom were delivered in full‐term . (2) maternal and infant follow‐up:five cases were lost to follow‐up ,the rest were followed up for 6~144 months ,twelve cases were alive and ten cases were dead . There were nineteen live births in twenty seven cases . The Apgar scores for the 19 cases were greater than seven points after delivery ,they are all still alive . Among them we did not find any history of fetal malformation ,dysphasia ,leukemia . Conclusion Should leukemia pa‐tients in remission be careful about pregnancy ,there may be a good pregnancy outcome . There is risk as result of leukemia and the treatment for the leukemia to the fetus and pregnant women ,needing to be in a general hospital capable of the comprehensive treatment and supervision .