CAJ | 학술논문

将硝唑尼特溶解于二甲亚砜，均匀喷于膨化饲料外涂油膜制成药物饲料，每天按鱼体重的50、100、150 mg·kg－1给药，连续给药6 d。用同步孵出的刺激隐核虫感染子按10000个·尾－1鱼感染鱼体，定期检查鱼体鳃、体表和鳍上滋养体数量。150 mg·kg－1组鱼体经4 d 给药鱼体全部死亡，50、100 mg·kg－1组连续6 d 给药鱼体正常。刺激隐核虫感染子对试验大黄鱼能大量感染，在不同给药量组间及是否给药组间的感染差异不明显，表明大黄鱼口服硝唑尼特不能有效预防刺激隐核虫的感染。
장초서니특용해우이갑아풍，균균분우팽화사료외도유막제성약물사료，매천안어체중적50、100、150 mg·kg－1급약，련속급약6 d。용동보부출적자격은핵충감염자안10000개·미－1어감염어체，정기검사어체새、체표화기상자양체수량。150 mg·kg－1조어체경4 d 급약어체전부사망，50、100 mg·kg－1조련속6 d 급약어체정상。자격은핵충감염자대시험대황어능대량감염，재불동급약량조간급시부급약조간적감염차이불명현，표명대황어구복초서니특불능유효예방자격은핵충적감염。
Efficacy of nitazoxanide (NTZ)by oral administration to Pseudosciaena crocea for the Cryptocaryon irritans infection was studied.NTZ was first-dissolved in dimethyl sulfoxide to be sprayed evenly on an extruded fish meal,which was,then,coated with a thin oil film.The meal was fed to the fish every day at the rates of 50, 100 or 150 mg per kg of the fish body weight.The treatments lasted 6 days.At the same time,simultaneously hatched theronts were introduced to infect the fish at a rate of 10 000 per P .crocea.Subsequently,the numbers of trophonts appeared on the gill,skin and fins of each fish were monitored regularly.After the 6-day treatments,all P .crocea were infected with thetheronts in large numbers,and the fish fed with 150 mg·kg-1 diet died,while the others survived.The oral NTZ treatment apparently did not prevent P .crocea from being infected by C.irritans .