中华脑科疾病与康复杂志(电子版)
中華腦科疾病與康複雜誌(電子版)
중화뇌과질병여강복잡지(전자판)
Chinese Journal of Brain Diseases and Rehabilitatin (Electronic Edition)
2015年
4期
222-225
,共4页
何毅%陶晶%纪涛%李维平
何毅%陶晶%紀濤%李維平
하의%도정%기도%리유평
卒中%近期预后%和肽素
卒中%近期預後%和肽素
졸중%근기예후%화태소
Stroke%Prognosis%Copeptin
目的:探讨急性缺血性脑卒中患者治疗前血浆和肽素水平与近期预后的相关性。方法随机选取深圳市第二人民医院2013年6~9月的急性缺血性脑卒中患者100例作为试验组,50例健康体检者为对照组,测定两组治疗前与治疗30 d后的血浆和肽素水平,用健康调查简表( SF-36)及美国国立卫生研究院卒中量表( NIHSS)的降低率评估30 d后的近期预后情况。运用SPSS 20.0软件包处理数据。结果治疗前试验组的血浆和肽素水平明显高于对照组[(439.03±210.91) pg/ml vs.(54.91±18.65)pg/ml,t=2.873,P<0.01]。 NIHSS结果:治疗前血浆和肽素水平越高,NIHSS降低率越小,甚至出现NIHSS值升高情况,试验组根据减少的NIHSS评分的百分数分为5个亚组,各亚组预后情况与患者治疗前和肽素水平呈负相关( r值分别为-0.661、-0.587、-0.734、-0.684、-0.632,均P<0.001)。 SF-36结果:预后情况与患者治疗前和肽素水平呈负相关( r 值分别为-0.673、-0.661、-0.715、-0.587、-0.734、-0.687、-0.635、-0.703,均P<0.001)。结论急性缺血性脑卒中患者治疗前的血浆和肽素水平越高,近期预后越差。
目的:探討急性缺血性腦卒中患者治療前血漿和肽素水平與近期預後的相關性。方法隨機選取深圳市第二人民醫院2013年6~9月的急性缺血性腦卒中患者100例作為試驗組,50例健康體檢者為對照組,測定兩組治療前與治療30 d後的血漿和肽素水平,用健康調查簡錶( SF-36)及美國國立衛生研究院卒中量錶( NIHSS)的降低率評估30 d後的近期預後情況。運用SPSS 20.0軟件包處理數據。結果治療前試驗組的血漿和肽素水平明顯高于對照組[(439.03±210.91) pg/ml vs.(54.91±18.65)pg/ml,t=2.873,P<0.01]。 NIHSS結果:治療前血漿和肽素水平越高,NIHSS降低率越小,甚至齣現NIHSS值升高情況,試驗組根據減少的NIHSS評分的百分數分為5箇亞組,各亞組預後情況與患者治療前和肽素水平呈負相關( r值分彆為-0.661、-0.587、-0.734、-0.684、-0.632,均P<0.001)。 SF-36結果:預後情況與患者治療前和肽素水平呈負相關( r 值分彆為-0.673、-0.661、-0.715、-0.587、-0.734、-0.687、-0.635、-0.703,均P<0.001)。結論急性缺血性腦卒中患者治療前的血漿和肽素水平越高,近期預後越差。
목적:탐토급성결혈성뇌졸중환자치료전혈장화태소수평여근기예후적상관성。방법수궤선취심수시제이인민의원2013년6~9월적급성결혈성뇌졸중환자100례작위시험조,50례건강체검자위대조조,측정량조치료전여치료30 d후적혈장화태소수평,용건강조사간표( SF-36)급미국국립위생연구원졸중량표( NIHSS)적강저솔평고30 d후적근기예후정황。운용SPSS 20.0연건포처리수거。결과치료전시험조적혈장화태소수평명현고우대조조[(439.03±210.91) pg/ml vs.(54.91±18.65)pg/ml,t=2.873,P<0.01]。 NIHSS결과:치료전혈장화태소수평월고,NIHSS강저솔월소,심지출현NIHSS치승고정황,시험조근거감소적NIHSS평분적백분수분위5개아조,각아조예후정황여환자치료전화태소수평정부상관( r치분별위-0.661、-0.587、-0.734、-0.684、-0.632,균P<0.001)。 SF-36결과:예후정황여환자치료전화태소수평정부상관( r 치분별위-0.673、-0.661、-0.715、-0.587、-0.734、-0.687、-0.635、-0.703,균P<0.001)。결론급성결혈성뇌졸중환자치료전적혈장화태소수평월고,근기예후월차。
Objective To explore the correlation between plasma copeptin level before treatment and recent prognosis in patients with acute ischemic stroke .Methods One hundred patients with acute ischemic stroke from Shenzhen Second People′s Hospital in June 2013 to September 2013 were randomly selected as the experimental group , and 50 healthy people as control group , plasma copeptin levels were measured before treatment and 30 days after treatment in both groups ,the MOS item short from health survey ( SF-36 ) and National institute of health stroke scale ( NIHSS ) reduction rate were used to evaluate the prognosis after 30 days.SPSS 20.0 software package was used for data processing .Results Plasma copeptin levels before treatment of the experimental group was significantly higher than that of the control group [(439.03 ±210.91)pg/ml vs.(54.91 ±18.65)pg/ml,t=2.873,P<0.01].The higher plasma copeptin lever before treatment was,the smaller the NIHSS reduction rate was ,even the NIHSS value increased ,the prognosis and peptide levels before treatment were inversely correlated ( r values were -0.661 ,-0.587 ,-0.734 ,-0.684 ,-0.632 , respectively , all P<0.001 ) .The SF-36 table was negatively correlated with peptide hormone levels before treatment ( r values were -0.673 , -0.661 , -0.715 , -0.587 , -0.734 ,-0.687 ,-0.635 ,-0.703 ,all P<0.001 ) .Conclusion The higher plasma copeptin level in patients with acute ischemic stroke before treatment is ,the poorer recent prognosis is .