CAJ | 학술논문

目的：探讨重组人生长激素(rhGH)对改善早产儿脑损伤的疗效。方法：将脑损伤早产儿70例分为治疗组和对照组。对照组给予常规治疗；治疗组除常规治疗外，给予rhGH治疗，比较两组新生儿神经行为测定(NBNA)评分及脑干听觉诱发电位(ABR)。结果：治疗组 NBNA 评分明显优于对照组。治疗组 ABR 异常发生率明显低于对照组(P＜0.05)。结论：rhGH可保护和修复受损伤神经细胞，有效改善脑损伤早产儿的预后，促进早产儿神经行为发育。
목적：탐토중조인생장격소(rhGH)대개선조산인뇌손상적료효。방법：장뇌손상조산인70례분위치료조화대조조。대조조급여상규치료；치료조제상규치료외，급여rhGH치료，비교량조신생인신경행위측정(NBNA)평분급뇌간은각유발전위(ABR)。결과：치료조 NBNA 평분명현우우대조조。치료조 ABR 이상발생솔명현저우대조조(P＜0.05)。결론：rhGH가보호화수복수손상신경세포，유효개선뇌손상조산인적예후，촉진조산인신경행위발육。
Objective:To explore the improvement curative effect of recombinant human growth homorm on the premature infant with brain injury.Methods:70 cases with premature infant with brain injury were divided into the rhGH treatment group and the control group.The control group were given the conventional treatment.The rhGH treatment group were given rhGH treatment in addition to the conventional treatment.The neonatal behavioral neurological assessment(NBNA) scores and auditory brainstem response(ABR) of the two groups were compared.Results:The NBNA scores of the rhGH treatment group was obviously better than that of the control group.The abnormal incidence of ABR in the rhGH treatment group was obviously lower than that of the control group(P<0.05).Conclusion:Recombinant human growth homorm could protect and repair the damaged neurons and improve the prognosis of premature brain damage effectively and promote the neurobehavioral development of premature.