CAJ | 학술논문

目的：探讨妊娠相关血浆蛋白A（PAPP-A）、VEGF对妊娠高血压综合症关系诊断价值。方法：选择50例妊高症孕妇为研究组，另选50例正常孕妇为对照组。妊高症组按照严重程度分为轻、中、重三组，比较各组PAPP-A、VEGF含量。结果：妊高症组PAPP-A显著高于对照组，组间比较差异有统计学意义，随妊高症程度升高，PAPP-A亦呈增高趋势。妊高症组VEGF显著高于对照组，组间比较差异有统计学意义，但轻中重三组VEGF组间比较差异无统计学意义，无明显变化趋势。结论：妊娠高血压综合症孕妇其PAPP-A、VEGF含量升高，且PAPP-A与妊高症严重程度呈正相关，PAPP-A、VEGF含量可以作为妊高症监测指标。
목적：탐토임신상관혈장단백A（PAPP-A）、VEGF대임신고혈압종합증관계진단개치。방법：선택50례임고증잉부위연구조，령선50례정상잉부위대조조。임고증조안조엄중정도분위경、중、중삼조，비교각조PAPP-A、VEGF함량。결과：임고증조PAPP-A현저고우대조조，조간비교차이유통계학의의，수임고증정도승고，PAPP-A역정증고추세。임고증조VEGF현저고우대조조，조간비교차이유통계학의의，단경중중삼조VEGF조간비교차이무통계학의의，무명현변화추세。결론：임신고혈압종합증잉부기PAPP-A、VEGF함량승고，차PAPP-A여임고증엄중정도정정상관，PAPP-A、VEGF함량가이작위임고증감측지표。
Objective: To investigate the relationship between PAPP-A and VEGF in pregnancy induced hypertension syndrome.Methods:50 cases of PIH pregnant women as the study group, while 50 healthy pregnant women as control group. The patients with hypertension were divided into three groups according to the severity of the disease, in which the contents of VEGF and PAPP-A were compared.Results: PAPP-A was signiifcantly higher in the patients with pregnancy induced hypertension than in the control group, the difference was statistically signiifcant, with the increase of the degree of pregnancy induced hypertension, PAPP-A was also increased. VEGF was significantly higher in the patients with pregnancy induced hypertension than in the control group, the difference was statistically signiifcant, but there was no signiifcant difference between the groups in the three groups, no signiifcant change trend.Conclusion: The contents of PAPP-A and VEGF in pregnant women with pregnancy induced hypertension, and PAPP-A was positively correlated with the severity of hypertension. VEGF and PAPP-A were used as the indexes for the monitoring of pregnancy induced hypertension.