当代医学
噹代醫學
당대의학
Contemporary Medicine
2015年
27期
58-59
,共2页
系统性红斑狼疮%肺动脉高压%雷诺现象%肺间质纤维化
繫統性紅斑狼瘡%肺動脈高壓%雷諾現象%肺間質纖維化
계통성홍반랑창%폐동맥고압%뢰낙현상%폐간질섬유화
Systemic lupus erythematosus%Pulmonary arterial hypertension%Raynaud's phenomenon%Pulmonary ifbrosis
目的：分析系统性红斑狼疮(SLE)合并肺动脉高压（PAH）的相关高危因素。方法选取SLE患者35例，其中17例合并PAH的患者为观察组，18例未合并PAH的患者为对照组，对2组的疾病活动性、临床表现、自身抗体、补体等进行比较。结果观察组中的雷诺现象（64.7%）、疾病活动（70.1%）、心包积液(41.2%)、肺间质纤维化(58.8%)患者比例均明显高于对照组，差异具有统计学意义（P<0.05）。结论雷诺现象、疾病活动、心包积液、肺间质纤维化是SLE患者易并发PAH的高危因素,与自身抗体无关。
目的：分析繫統性紅斑狼瘡(SLE)閤併肺動脈高壓（PAH）的相關高危因素。方法選取SLE患者35例，其中17例閤併PAH的患者為觀察組，18例未閤併PAH的患者為對照組，對2組的疾病活動性、臨床錶現、自身抗體、補體等進行比較。結果觀察組中的雷諾現象（64.7%）、疾病活動（70.1%）、心包積液(41.2%)、肺間質纖維化(58.8%)患者比例均明顯高于對照組，差異具有統計學意義（P<0.05）。結論雷諾現象、疾病活動、心包積液、肺間質纖維化是SLE患者易併髮PAH的高危因素,與自身抗體無關。
목적：분석계통성홍반랑창(SLE)합병폐동맥고압（PAH）적상관고위인소。방법선취SLE환자35례，기중17례합병PAH적환자위관찰조，18례미합병PAH적환자위대조조，대2조적질병활동성、림상표현、자신항체、보체등진행비교。결과관찰조중적뢰낙현상（64.7%）、질병활동（70.1%）、심포적액(41.2%)、폐간질섬유화(58.8%)환자비례균명현고우대조조，차이구유통계학의의（P<0.05）。결론뢰낙현상、질병활동、심포적액、폐간질섬유화시SLE환자역병발PAH적고위인소,여자신항체무관。
Objective To analyze the high risk factors of systemic lupus erythematosus (SLE)with pulmonary arterial hypertension(PAH). Methods 35 patients with SLE were selected, 17 cases of merger PAH were as observation group, 18 cases of unincorporated PAH were as control group, disease activity,clinical features,autoantibodies complement of two groups were compared. Results In the observation group, raynaud's phenomenon(64.7%), disease activity(70.1%), pericardial effusion(41.2%), pulmonary interstitial ifbrosis(58.8%), are all apparently higher than the control group, the difference was statistically signiifcant(P<0.05). Conclusion Renault phenomenon, disease activity, pericardial effusion, pulmonary interstitial ifbrosis is easy to SLE patients complicated with PAH of the risk factors, has no relation to autoantibodies.
