CAJ | 학술논문

目的：分析、总结 AIDS 合并肺癌的临床及 CT 表现特点，提高对 AIDS 合并肺癌的认识。方法：回顾性分析经临床病理证实的17例 AIDS 合并肺癌患者的临床及 CT 表现。结果：AIDS 合并肺癌以中年男性多见，常合并肺部感染。CT 多表现为外周分布的类圆形、分叶状软组织肿块，多合并纵隔和／或肺门淋巴结肿大。伴有肺部感染者与不伴肺部感染者相比，在肿块分布、外形、密度、邻近肺野及胸膜改变、肿大淋巴结方面差异均无统计学意义（Fisher 确切概率法， P ＞0．05），但肿块较大、伴有胸水在两者间差异有统计学意义（t 检验，P ＝0．02；Fisher 确切概率法，P ＝0．04）。结论：中年男性 AIDS 患者伴有肺部机会性感染时，若肿块较大、出现胸水且对症处理后效果不明显时，应考虑到肺癌的可能。
목적：분석、총결 AIDS 합병폐암적림상급 CT 표현특점，제고대 AIDS 합병폐암적인식。방법：회고성분석경림상병리증실적17례 AIDS 합병폐암환자적림상급 CT 표현。결과：AIDS 합병폐암이중년남성다견，상합병폐부감염。CT 다표현위외주분포적류원형、분협상연조직종괴，다합병종격화／혹폐문림파결종대。반유폐부감염자여불반폐부감염자상비，재종괴분포、외형、밀도、린근폐야급흉막개변、종대림파결방면차이균무통계학의의（Fisher 학절개솔법， P ＞0．05），단종괴교대、반유흉수재량자간차이유통계학의의（t 검험，P ＝0．02；Fisher 학절개솔법，P ＝0．04）。결론：중년남성 AIDS 환자반유폐부궤회성감염시，약종괴교대、출현흉수차대증처리후효과불명현시，응고필도폐암적가능。
Objectives:The purpose of this study was to analyze and summarize the clinical and CT features of lung cancer in patients with AIDS,in order to improve the knowledge of this complication in terms of early diagnosis.Methods:Medical data of pathologically proved lung cancer in patient with AIDS in the affiliated Shanghai public health clinical center of the Fudan university were retrospectively analyzed during the period from November 2011 to June 2015,including clinical and pathological data and CT features.All data was analyzed by means of t-test and chi-square test of four-fold table.Re-sults:AIDS patients complicated with lung cancer were most commonly seen in middle age male patients,often accompanied by pulmonary infection.Manifestations of CT were as follows:round or lobular masses or nodules of soft tissue density mainly in peripheral airspace,often accompanied with mediastinal or hilar lymphadenopathy.There were no significant differences between patients with and without pulmonary infections on mass locations,contour,density,adjacent lung field and pleural changes,and lymphadenopathy (Fisher exact,all P >0.05 ),except for bigger masses with pleural effusion (t test,P =0.02;Fisher exact,P =0.04).Conclusion:Big lung mass with hydrothorax and inefficacious opportunistic pulmona-ry infections in middle aged AIDS male patient should lead to a diagnosis of lung cancer.