CAJ | 학술논문

目的：大鼠肝脏给予康派特?医用胶或泰绫?可吸收性止血纱布的安全性比较。方法：手术组大鼠肝脏定量切除后，给予康派特?医用胶或泰绫?可吸收性止血纱布止血，空白对照组大鼠不进行手术。术后动物进行临床症状观察，体重、摄食量测定，肛温、血常规、血清生化学、脏器重量和组织病理学检查。结果：各项指标均未见与康派特?医用胶和泰绫相关毒性反应；3个月组织病理学检查可见胶体被纤维结缔组织分割包裹。结论：本试验条件下，未见康派特?医用胶和泰绫?可吸收性止血纱布对大鼠机体有毒性作用，康派特?医用胶在大鼠体内3个月开始降解。
목적：대서간장급여강파특?의용효혹태릉?가흡수성지혈사포적안전성비교。방법：수술조대서간장정량절제후，급여강파특?의용효혹태릉?가흡수성지혈사포지혈，공백대조조대서불진행수술。술후동물진행림상증상관찰，체중、섭식량측정，항온、혈상규、혈청생화학、장기중량화조직병이학검사。결과：각항지표균미견여강파특?의용효화태릉상관독성반응；3개월조직병이학검사가견효체피섬유결체조직분할포과。결론：본시험조건하，미견강파특?의용효화태릉?가흡수성지혈사포대대서궤체유독성작용，강파특?의용효재대서체내3개월개시강해。
Comparing the safety of Compont? medical adhesiveand TISTAT? absorbable styptic gauze used in rat liver. Methods:Ratsin operation groupwere resecteda quantitativeliverandstopped blooding with Compont? medical adhesive or TISTAT? absorbable styptic gauze.Blank group took nothing treatment.Clinical observations, body weight, food intake, rectal temperature, blood routine, serum biochemical, organ weight and histopathological examination were performed on Postoperative animals. Results:No toxic effect was observed in all indexes related with Compont? medical adhesive or TISTAT? Absorbable styptic gauze. Histopathological examination after administration for 3 months showed the colloid was gradually divided by fibrous connective tissue. Conclusions:The Compont? medical adhesiveand TISTAT? absorbable styptic gauze were no toxic effect on the body of rats under the experimental conditions, and the Compont? medical adhesivebegan to degrade in rats after 3 months.