临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
Chinese Journal of Clinical Rational Drug Use
2015年
26期
27-28
,共2页
中药外洗%外阴阴道假丝酵母菌病%复发%预防
中藥外洗%外陰陰道假絲酵母菌病%複髮%預防
중약외세%외음음도가사효모균병%복발%예방
Chinese medicine%Vulvovaginal candidiasis%Recurrence%Prevention
目的：观察中药外洗对减少外阴阴道假丝酵母菌病复发的临床效果。方法选取120例外阴阴道假丝酵母菌病患者，除去失访的13例患者，其余随机分为观察组54例与对照组53例。观察组与对照组均给克霉唑阴道片1枚，阴道用药，观察组同时予中药煎液阴道外用灌洗。随访6个月，比较2组复发情况。结果观察组总有效率79.6％，对照组总有效率73.6％，2组比较差异无统计学意义（P ﹥0.05）。观察组随访6个月内复发11例，复发率25.6％；对照组随访6个月复发28例，复发率71.8％，观察组复发率明显低于对照组，差异有统计学意义（ P ﹤0.05）。结论采用中医外洗能显著降低外阴阴道假丝酵母菌病治疗后的复发率，但仍需扩大样本进一步观察其疗效和安全性。
目的：觀察中藥外洗對減少外陰陰道假絲酵母菌病複髮的臨床效果。方法選取120例外陰陰道假絲酵母菌病患者，除去失訪的13例患者，其餘隨機分為觀察組54例與對照組53例。觀察組與對照組均給剋黴唑陰道片1枚，陰道用藥，觀察組同時予中藥煎液陰道外用灌洗。隨訪6箇月，比較2組複髮情況。結果觀察組總有效率79.6％，對照組總有效率73.6％，2組比較差異無統計學意義（P ﹥0.05）。觀察組隨訪6箇月內複髮11例，複髮率25.6％；對照組隨訪6箇月複髮28例，複髮率71.8％，觀察組複髮率明顯低于對照組，差異有統計學意義（ P ﹤0.05）。結論採用中醫外洗能顯著降低外陰陰道假絲酵母菌病治療後的複髮率，但仍需擴大樣本進一步觀察其療效和安全性。
목적：관찰중약외세대감소외음음도가사효모균병복발적림상효과。방법선취120예외음음도가사효모균병환자，제거실방적13례환자，기여수궤분위관찰조54례여대조조53례。관찰조여대조조균급극매서음도편1매，음도용약，관찰조동시여중약전액음도외용관세。수방6개월，비교2조복발정황。결과관찰조총유효솔79.6％，대조조총유효솔73.6％，2조비교차이무통계학의의（P ﹥0.05）。관찰조수방6개월내복발11례，복발솔25.6％；대조조수방6개월복발28례，복발솔71.8％，관찰조복발솔명현저우대조조，차이유통계학의의（ P ﹤0.05）。결론채용중의외세능현저강저외음음도가사효모균병치료후적복발솔，단잉수확대양본진일보관찰기료효화안전성。
Objective To observe the effect of traditional Chinese medicine external treatment for preventing recur-rence of Vulvovaginal candidiasis. Methods 107 cases of Vulvovaginal candidiasis patients were divided into observation group(54 cases)and control group(53 cases). All the patients were first diagnosed as Vulvovaginal candidiasis. Clotrimazole Vaginal Tablet was given only one time. The patients of observation group were given the external treatment of Chinese medicine vaginal lavage once before vaginal tablet used. And the patients would recieve external washing 20 minutes every night for the following 5 days. The patients of control group would only treated with Clotrimazole Vaginal Tablet once. All the patients were followed up for 6 months. Results The total effective rate of the observation group was 79. 6% ,the total effective rate was 73. 6% in the control group,the difference was not statistically significant(P ﹥ 0. 05). Follow up for 6 months,the recurrence rate of the observation group was 25. 6% ,significantly lower than the control group of 71. 8% ,the difference was statistically significant(P ﹤ 0. 05). Conclusion For relapse prevention of Vulvovaginal candidiasis,the traditional Chinese medicine ex-ternal treatment can effectively reduce the recurrence of Vulvovaginal candidiasis,but there still need expanding the cases to in-vestigate the efficacy and safety of traditional Chinese medicine.
