CAJ | 학술논문

目的：探讨丙泊酚联合芬太尼用于肝硬化患者胃镜诊疗中的临床效果，评价其安全性。方法选取2013年4月至2015年4月我院消化内科收治的48例肝硬化患者，均采用胃镜诊疗，按麻醉方法不同分为观察组（24例）和对照组（24例），观察组行丙泊酚联合芬太尼麻醉，对照组单用丙泊酚麻醉，对比两组患者的临床诊疗效果及不良反应发生率。结果观察组麻醉阻滞时间优于对照组（P<0.05），且手术时间、不良反应发生率及诊疗后SpO2、HR、BP等指标均显著低于对照组（P<0.05），差异有统计学意义。结论在肝硬化患者胃镜诊疗中应用丙泊酚联合芬太尼麻醉，疗效确切，安全可靠，可改善脉搏血氧饱和度、心率、血压，降低不良反应发生率，值得临床应用与推广。
목적：탐토병박분연합분태니용우간경화환자위경진료중적림상효과，평개기안전성。방법선취2013년4월지2015년4월아원소화내과수치적48례간경화환자，균채용위경진료，안마취방법불동분위관찰조（24례）화대조조（24례），관찰조행병박분연합분태니마취，대조조단용병박분마취，대비량조환자적림상진료효과급불량반응발생솔。결과관찰조마취조체시간우우대조조（P<0.05），차수술시간、불량반응발생솔급진료후SpO2、HR、BP등지표균현저저우대조조（P<0.05），차이유통계학의의。결론재간경화환자위경진료중응용병박분연합분태니마취，료효학절，안전가고，가개선맥박혈양포화도、심솔、혈압，강저불량반응발생솔，치득림상응용여추엄。
Objective To explore clinical efficacy of propofol combined fentanyl for gastroscopic diag-nosis and treatment of patients with liver cirrhosis and to evaluate the safety. Method Forty eight patients with liver cirrhosis in the Department of Gastroenterology of our hospital from April, 2013 to April, 2015 were se-lected, and all of them underwent gastroscopic diagnosis and treatment. The patients were randomly divided into observation group (24 cases) and control group (24 cases) according to the different anesthetic methods. Patients in observation group were subjected to propofol combined fentanyl anesthesia, and patients in control group were subjected to single propofol anesthesia. Clinical power of diagnosis and treatment and incidence of adverse reactions in two groups were compared. Result The duration of anesthesia blockade of patients in ob-servation group was better than that of patients in control group (P<0.05). In observation group, the operation duration, the incidence of adverse reactions including SpO2, heart rate, blood pressure, and other indexes after diagnosis was significantly lower than those of patients in control group (P<0.05). Conclusion Propofol com-bined fentanyl anesthesia for gastroscopic diagnosis and treatment of patients with cirrhosis was efficacy, safe, and reliable.