临床和实验医学杂志
臨床和實驗醫學雜誌
림상화실험의학잡지
Journal of Clinical and Experimental Medicine
2015年
17期
1443-1445
,共3页
冠心病%动脉硬化指数%尿微量白蛋白%冠状动脉狭窄程度
冠心病%動脈硬化指數%尿微量白蛋白%冠狀動脈狹窄程度
관심병%동맥경화지수%뇨미량백단백%관상동맥협착정도
Coronary heart disease%Ambulatory arterial stiffness index%Microalbuminuria%Coronary artery stenosis degree
目的：研究动态动脉硬化指数（ AASI）和尿微量白蛋白（ MAU）与冠心病患者冠状动脉狭窄程度的相关性。方法选择冠心病130例患者，根据冠状动脉造影检查结果分为单支病变组（56例）、双支病变组（41例）、多支病变组（33例），同时选择冠脉正常患者为正常对照组（60例）。测定和比较各组的AASI、MAU；以Gensini积分表示冠状动脉狭窄程度，评价Gensini积分与AASI、MAU的相关性。结果多支病变组的AASI、MAU水平最高，其次为双支病变组、单支病变组，组间比较差异有统计学意义（ P <0.05），冠心病组AASI、MAU水平均显著高于正常对照组（ P <0.05）。相关性分析显示Gensini积分与AASI、MAU均呈显著正相关（ r =0.674，0.732，P <0.01）。结论AASI和MAU水平随冠脉病变支数的增加而上升，AASI和MAU水平与冠状动脉狭窄程度呈显著的正相关，可作为评价病变严重程度的参考指标。
目的：研究動態動脈硬化指數（ AASI）和尿微量白蛋白（ MAU）與冠心病患者冠狀動脈狹窄程度的相關性。方法選擇冠心病130例患者，根據冠狀動脈造影檢查結果分為單支病變組（56例）、雙支病變組（41例）、多支病變組（33例），同時選擇冠脈正常患者為正常對照組（60例）。測定和比較各組的AASI、MAU；以Gensini積分錶示冠狀動脈狹窄程度，評價Gensini積分與AASI、MAU的相關性。結果多支病變組的AASI、MAU水平最高，其次為雙支病變組、單支病變組，組間比較差異有統計學意義（ P <0.05），冠心病組AASI、MAU水平均顯著高于正常對照組（ P <0.05）。相關性分析顯示Gensini積分與AASI、MAU均呈顯著正相關（ r =0.674，0.732，P <0.01）。結論AASI和MAU水平隨冠脈病變支數的增加而上升，AASI和MAU水平與冠狀動脈狹窄程度呈顯著的正相關，可作為評價病變嚴重程度的參攷指標。
목적：연구동태동맥경화지수（ AASI）화뇨미량백단백（ MAU）여관심병환자관상동맥협착정도적상관성。방법선택관심병130례환자，근거관상동맥조영검사결과분위단지병변조（56례）、쌍지병변조（41례）、다지병변조（33례），동시선택관맥정상환자위정상대조조（60례）。측정화비교각조적AASI、MAU；이Gensini적분표시관상동맥협착정도，평개Gensini적분여AASI、MAU적상관성。결과다지병변조적AASI、MAU수평최고，기차위쌍지병변조、단지병변조，조간비교차이유통계학의의（ P <0.05），관심병조AASI、MAU수평균현저고우정상대조조（ P <0.05）。상관성분석현시Gensini적분여AASI、MAU균정현저정상관（ r =0.674，0.732，P <0.01）。결론AASI화MAU수평수관맥병변지수적증가이상승，AASI화MAU수평여관상동맥협착정도정현저적정상관，가작위평개병변엄중정도적삼고지표。
Objective To evaluate the relationship between ambulatory arterial stiffness index( AASI),microalbuminuria( MAU)and the extent of coronary artery stenosis. Methods The data of patients with coronary angiography in our hospital were selected into this study. Of which 130 cases were diagnosed with coronary heart disease,and they were divided into single-vessel disease group(56 cases),two-vessel dis-ease group(41 cases)and multiple-vessel disease group(33 cases)according with the results of coronary arteriography. 60 cases with no coro-nary heart disease at the same period were selected as normal control group. The AASI,MAU of two groups were determined and compared. The extent of coronary artery stenosis was signified with Gensini score. The relationship of AASI,MAU and Gensini score was evaluated. Results The AASI,MAU of multiple-vessel disease group were highest,and followed with two-vessel disease group,single -vessel disease group. The AA-SI,MAU of three disease groups were significantly different( P <0. 5),and were significantly higher than normal control group( P < 0. 05). There were significant positive correlation between Gensini score and AASI,MAU( r =0. 674,r =0. 732,P <0. 01). Conclusion The AASI, MAU levels increased with the increase of the coronary artery lesion counts and there were positive correlation between the extent of coronary artery stenosis and AASI,MAU levels,i can be valued as the severity of the reference index.
