CAJ | 학술논문

目的：观察鼠神经生长因子（NGF）改善蛛网膜下腔出血性认知功能障碍的临床疗效。方法：将蛛网膜下腔出血性认知障碍的患者随机分为两组，治疗组18例，予神经生长因子18μg，肌注，1次/天，4周为1疗程，对照组12例，予胞磷胆碱注射液0.5静点，4周为1疗程，两组患者均于治疗2个疗程后复查各项指标。结果：两组患者治疗后MMSE、ADL、QOL与治疗前比较差异均有统计学意义（P＜0.05），治疗后两组间MMSE、ADL、QOL比较，治疗组优于对照组（P＜0.05）。结论：鼠神经生长因子治疗蛛网膜下腔出血性认知功能障碍可以改善其认知功能。
목적：관찰서신경생장인자（NGF）개선주망막하강출혈성인지공능장애적림상료효。방법：장주망막하강출혈성인지장애적환자수궤분위량조，치료조18례，여신경생장인자18μg，기주，1차/천，4주위1료정，대조조12례，여포린담감주사액0.5정점，4주위1료정，량조환자균우치료2개료정후복사각항지표。결과：량조환자치료후MMSE、ADL、QOL여치료전비교차이균유통계학의의（P＜0.05），치료후량조간MMSE、ADL、QOL비교，치료조우우대조조（P＜0.05）。결론：서신경생장인자치료주망막하강출혈성인지공능장애가이개선기인지공능。
Objective: To observe the mice nerve growth factor(NGF) to improve clinical curative effect of subarachnoid hemorrhagic cognitive dysfunction.Methods: Subarachnoid hemorrhagic cognitive impairment of patients were randomly divided into two groups: treatment group (18 cases,to the nerve growth factor and 18μg,intramuscular injection,1 time/day,4 weeks for 1 course of treatment,12 cases in the control group,40 mg still point to the ganglioside,4 weeks for 1 course of treatment,two groups of patients in the treatment after two courses of review of the indicators.Results:Two groups of patients after treatment MMSE,ADL,QOL compared with before treatment difference had statistical significance (P<0.05) between the two groups after treatment MMSE,ADL,QOL comparison,the treatment group is better than that of control group(P<0.05).Conclusion: Mmouse nerve growth factor in treatment of subarachnoid cognitive dysfunction can improve the cognitive function.