中国医药导刊
中國醫藥導刊
중국의약도간
Chinese Journal of Medical Guide
2015年
8期
821-823
,共3页
蒲地蓝消炎口服液%复发性口腔溃疡
蒲地藍消炎口服液%複髮性口腔潰瘍
포지람소염구복액%복발성구강궤양
Pudilan%Recurrent oral ulcers
目的：观察蒲地蓝口服液治疗复发性口腔溃疡（ROU）的临床疗效。方法：选取2014年2～9月在天津市南开医院口腔科就诊的ROU患者60例，采用随机数字表法分为实验组和对照组，各30例。实验组口服维生素C和复合维生素B，并用蒲地蓝口服液含服，对照组口服维生素C和复合维生素B。观察1至7天疗效（观察患者平均溃疡天数，疼痛指数），进行对比分析。结果：实验组溃疡愈合时间较对照组明显缩短（P=0.037＜0.05），治疗第三天溃疡疼痛指数较对照组明显减轻（P＜0.05），两组差异具有统计学意义,实验组较对照组疗效有统计学意义（P=0.043，P＜0.05）。实验中未出现明显不良反应而停药及不良黏膜着色现象。结论：采用蒲地蓝口服液治疗ROU效果显著，能缩短溃疡愈合时间，缓解局部症状，且无不良反应。
目的：觀察蒲地藍口服液治療複髮性口腔潰瘍（ROU）的臨床療效。方法：選取2014年2～9月在天津市南開醫院口腔科就診的ROU患者60例，採用隨機數字錶法分為實驗組和對照組，各30例。實驗組口服維生素C和複閤維生素B，併用蒲地藍口服液含服，對照組口服維生素C和複閤維生素B。觀察1至7天療效（觀察患者平均潰瘍天數，疼痛指數），進行對比分析。結果：實驗組潰瘍愈閤時間較對照組明顯縮短（P=0.037＜0.05），治療第三天潰瘍疼痛指數較對照組明顯減輕（P＜0.05），兩組差異具有統計學意義,實驗組較對照組療效有統計學意義（P=0.043，P＜0.05）。實驗中未齣現明顯不良反應而停藥及不良黏膜著色現象。結論：採用蒲地藍口服液治療ROU效果顯著，能縮短潰瘍愈閤時間，緩解跼部癥狀，且無不良反應。
목적：관찰포지람구복액치료복발성구강궤양（ROU）적림상료효。방법：선취2014년2～9월재천진시남개의원구강과취진적ROU환자60례，채용수궤수자표법분위실험조화대조조，각30례。실험조구복유생소C화복합유생소B，병용포지람구복액함복，대조조구복유생소C화복합유생소B。관찰1지7천료효（관찰환자평균궤양천수，동통지수），진행대비분석。결과：실험조궤양유합시간교대조조명현축단（P=0.037＜0.05），치료제삼천궤양동통지수교대조조명현감경（P＜0.05），량조차이구유통계학의의,실험조교대조조료효유통계학의의（P=0.043，P＜0.05）。실험중미출현명현불량반응이정약급불량점막착색현상。결론：채용포지람구복액치료ROU효과현저，능축단궤양유합시간，완해국부증상，차무불량반응。
Objective: To observe the clinical effect of Pudilan in the treatment of recurrent oral ulcer (ROU).Methods: A total of 60 patients admitted to the department of stomatology in Tianjin Nankai hospital from February to September in 2014 were selected.All the patients were randomly divided into experiment group and control group,each group of 30 patients.The experimental group was treated with vitamin C and vitamin B combined with Pudilan,the control group was treated with vitamin C and vitamin B.The clinical effect(duration,pain degree) of these two group was evaluated from one day to seven day after treatment.Results:The duration of treatment was significantly shorter than the control group(P=0.037<0.05),from the third day of treatment,the ulcer pain index was significantly reduced compared with the control group(P<0.05),the difference was statistically significant.No adverse reaction and mucosa staining appeared during the experiment.Conclusion:Pudilan has an obvious effect.It can shorten the duration of treatment, and it can also relieve local symptoms and reduce the incidence of adverse reactions.
