齐齐哈尔医学院学报
齊齊哈爾醫學院學報
제제합이의학원학보
Journal of Qiqihar University of Medicine
2015年
25期
3803-3804
,共2页
血液灌流%急腹症%感染性休克%死亡率
血液灌流%急腹癥%感染性休剋%死亡率
혈액관류%급복증%감염성휴극%사망솔
Hemoperfusion%Acute abdomen%Septic shock%Death rate
目的:观察常规治疗基础联合血液灌流( HP)治疗急腹症导致感染性休克的疗效。方法将30例患者随机分为治疗组和对照组,各15例,治疗组采用常规治疗联合HP,对照组采用常规治疗。通过治疗后比较两组患者治疗前后的平均动脉压(MAP)、氧合指数(PaO:/FiOz)、C一反应蛋白(CRP)、乳酸水平、降钙素原( PCT)、白细胞及心率,同时观察两组的住ICU天数、死亡率、不良反应及安全性。结果两组治疗后( MAP)、PaO2/FiO2、CRP、乳酸水平、PCT、白细胞、心率均较治疗前明显降低,差异有统计学意义;治疗组与对照组的死亡率分别为13.3%和40%,差异无统计学意义( P>0.05)。结论常规治疗联合HP治疗能更有效地清除炎症介质,改善感染性休克患者的预后,减低患者死亡率,缩短ICU住院时间,说明联合HP治疗急腹症感染性休克安全有效。
目的:觀察常規治療基礎聯閤血液灌流( HP)治療急腹癥導緻感染性休剋的療效。方法將30例患者隨機分為治療組和對照組,各15例,治療組採用常規治療聯閤HP,對照組採用常規治療。通過治療後比較兩組患者治療前後的平均動脈壓(MAP)、氧閤指數(PaO:/FiOz)、C一反應蛋白(CRP)、乳痠水平、降鈣素原( PCT)、白細胞及心率,同時觀察兩組的住ICU天數、死亡率、不良反應及安全性。結果兩組治療後( MAP)、PaO2/FiO2、CRP、乳痠水平、PCT、白細胞、心率均較治療前明顯降低,差異有統計學意義;治療組與對照組的死亡率分彆為13.3%和40%,差異無統計學意義( P>0.05)。結論常規治療聯閤HP治療能更有效地清除炎癥介質,改善感染性休剋患者的預後,減低患者死亡率,縮短ICU住院時間,說明聯閤HP治療急腹癥感染性休剋安全有效。
목적:관찰상규치료기출연합혈액관류( HP)치료급복증도치감염성휴극적료효。방법장30례환자수궤분위치료조화대조조,각15례,치료조채용상규치료연합HP,대조조채용상규치료。통과치료후비교량조환자치료전후적평균동맥압(MAP)、양합지수(PaO:/FiOz)、C일반응단백(CRP)、유산수평、강개소원( PCT)、백세포급심솔,동시관찰량조적주ICU천수、사망솔、불량반응급안전성。결과량조치료후( MAP)、PaO2/FiO2、CRP、유산수평、PCT、백세포、심솔균교치료전명현강저,차이유통계학의의;치료조여대조조적사망솔분별위13.3%화40%,차이무통계학의의( P>0.05)。결론상규치료연합HP치료능경유효지청제염증개질,개선감염성휴극환자적예후,감저환자사망솔,축단ICU주원시간,설명연합HP치료급복증감염성휴극안전유효。
Objective To investigate the effect of the conventional treatment combined with hemoperfusion( HP) in treating septic shock patients caused by acute abdomen.Methods 30 patients were randomly divided into treatment group and control group, 15 cases in each group, patients in treatment group used the conventional treatment combined with hemoperfusion, and patients in control group used conventional therapy only.Mean arterial pressure (MAP), oxygenationindex (PaO /FiOz), C reactive protein (CRP),lactic acid level,procalcitonin ( PCT) , white blood cell and heart rate were compared both at before and after the treatment between the two groups.ICU stay days, mortality, adverse reaction of treatment and the security were observed in the two groups.Results After treatment, the mean arterial pressure( MAP) ,oxygenation index ( PaO2/FiO2 ) , c-reactive protein (CRP), lactic acid level, Procalcitonin (PCT),white blood cell and heart rate of the two groups were significantly decreased, the differences were statistically significant.The mortality of treatment group and the control group were 13.3%and 40%respectively, the difference was not statistically significant ( P>0. 05).Conclusions The conventional treatment combined with HP therapy can effectively remove inflammatory mediators to improve the outcome in patients with septic shock, reduce the mortality of patients, short the duration of hospitalization in ICU, thus conventional treatmentcombined with HP in the treatment of septic shock caused by acute abdomen is safe and effective.