CAJ | 학술논문

目的：探讨血淀粉酶持续时间对急性胰腺炎合并代谢综合征预后的预测价值。方法选择急性胰腺炎患者150例,其中单纯胰腺炎患者50例,合并代谢综合征患者100例。合并代谢综合征患者中,血淀粉酶恢复正常时间超过5 d患者50例,5 d内恢复正常患者50例。150例急性胰腺炎患者出院后均随访1个月,对是否合并代谢综合征,其血淀粉酶及升高持续天数进行比较,同时统计合并代谢综合征患者,血淀粉酶恢复时间与血脂血糖水平变化情况以及发生并发症情况。结果合并代谢综合征患者血淀粉酶水平高于未合并代谢综合征患者(P<0．05),且血淀粉酶升高持续天数长于未合并代谢综合征患者(P<0．05)。血淀粉酶恢复时间超过5 d患者的总胆固醇、甘油三酯、空腹及餐后2 h血糖水平均高于5 d内恢复正常患者(P<0．05)。血淀粉酶恢复时间超过5 d患者,发生低蛋白血症、血糖异常、低钾血症、低钙血症及低镁血症的比例显著高于5 d内恢复正常患者( P<0．05)。结论急性胰腺炎合并代谢综合征患者的血淀粉酶持续升高时间越长,其越容易发生血脂、血糖代谢异常,治疗中应注意调节患者电解质。
목적：탐토혈정분매지속시간대급성이선염합병대사종합정예후적예측개치。방법선택급성이선염환자150례,기중단순이선염환자50례,합병대사종합정환자100례。합병대사종합정환자중,혈정분매회복정상시간초과5 d환자50례,5 d내회복정상환자50례。150례급성이선염환자출원후균수방1개월,대시부합병대사종합정,기혈정분매급승고지속천수진행비교,동시통계합병대사종합정환자,혈정분매회복시간여혈지혈당수평변화정황이급발생병발증정황。결과합병대사종합정환자혈정분매수평고우미합병대사종합정환자(P<0．05),차혈정분매승고지속천수장우미합병대사종합정환자(P<0．05)。혈정분매회복시간초과5 d환자적총담고순、감유삼지、공복급찬후2 h혈당수평균고우5 d내회복정상환자(P<0．05)。혈정분매회복시간초과5 d환자,발생저단백혈증、혈당이상、저갑혈증、저개혈증급저미혈증적비례현저고우5 d내회복정상환자( P<0．05)。결론급성이선염합병대사종합정환자적혈정분매지속승고시간월장,기월용역발생혈지、혈당대사이상,치료중응주의조절환자전해질。
Objective To evaluate the prognostic value of serum amylase duration in acute pancreatitis with metabolic syndrome. Methods A total of 150 cases with acute pancreatitis were chosen, including 50 cases with pancreatitis amylase returned to normal time, 50 cases whose recover time was over 5 days, and 50 cases were returned in 5 days;after discharge, all were followed one month, and whether with metabolic syndrome and blood amylase increases were compared for several days; meanwhile, serum amylase recovery time and blood lipid changes in blood glucose levels and the occurrence of complications in patients with metabolic syndrome were statistically analysed. Re-sults With metabolic syndrome, serum amylase levels were higher than patients without metabolic syndrome(P<0. 05), and the duration of increased serum amylase was longer than those without metabolic syndrome(P<0. 05). For patients whose serum amylase enzyme recovery time was more than 5 days, their total cholesterol, triglycerides, fasting glucose and 2-hour postprandial blood glucose levels were higher than those whose serum amylase returned to normal within 5 days(P<0. 05). For patients whose serum amylase recovery time was more than 5 days, the incidence of low albumin, glucose, the proportion of hypokalemia, hypocalcemia and hypomagnesemia was significantly higher than those whose serum amylase was normal in 5 days(P<0. 05). Conclusion In acute pancreatitis with metabolic syndrome, the more the duration of serum amylase rise, the more prone to blood lipid and glucose metabolism, so the electrolyte balance adjustment should be high-lighted in the treatment.