医疗卫生装备
醫療衛生裝備
의료위생장비
Chinese Medical Equipment Journal
2015年
9期
78-80
,共3页
左路广%马科%冯博%周素涛%李洁
左路廣%馬科%馮博%週素濤%李潔
좌로엄%마과%풍박%주소도%리길
胸腹水%高荧光细胞%恶性积液
胸腹水%高熒光細胞%噁性積液
흉복수%고형광세포%악성적액
hydrothorax and ascites%high-fluorescent cell%malignant effusion
目的：研究胸腹水高荧光细胞筛查恶性积液价值。方法：选取2014年1月至12月住院、门诊患者400例，收集临床诊断结果及胸腹水标本，选用Sysmex XE－5000血细胞分析仪检测高荧光细胞数并涂片染色镜检，运用受试者工作特征（receiver operating characteristic，ROC）曲线，分析研究胸腹水高荧光细胞筛查恶性积液的灵敏度、特异性、阳性似然比及阴性似然比，探讨高荧光细胞对恶性积液的诊断价值。结果：恶性肿瘤患者组高荧光细胞数明显高于非恶性肿瘤患者组（Z=－7.372，P<0.05），高荧光细胞数曲线下面积（area under curve，AUC）为0.801，灵敏度70.67%，特异性84.31%，阳性似然比4.50，阴性似然比0.35。结论：检测胸腹水高荧光细胞可用于恶性积液的筛查，当胸腹水标本高荧光细胞数临界值（cut－off值）≥68时，应进一步检查并跟踪随访。
目的：研究胸腹水高熒光細胞篩查噁性積液價值。方法：選取2014年1月至12月住院、門診患者400例，收集臨床診斷結果及胸腹水標本，選用Sysmex XE－5000血細胞分析儀檢測高熒光細胞數併塗片染色鏡檢，運用受試者工作特徵（receiver operating characteristic，ROC）麯線，分析研究胸腹水高熒光細胞篩查噁性積液的靈敏度、特異性、暘性似然比及陰性似然比，探討高熒光細胞對噁性積液的診斷價值。結果：噁性腫瘤患者組高熒光細胞數明顯高于非噁性腫瘤患者組（Z=－7.372，P<0.05），高熒光細胞數麯線下麵積（area under curve，AUC）為0.801，靈敏度70.67%，特異性84.31%，暘性似然比4.50，陰性似然比0.35。結論：檢測胸腹水高熒光細胞可用于噁性積液的篩查，噹胸腹水標本高熒光細胞數臨界值（cut－off值）≥68時，應進一步檢查併跟蹤隨訪。
목적：연구흉복수고형광세포사사악성적액개치。방법：선취2014년1월지12월주원、문진환자400례，수집림상진단결과급흉복수표본，선용Sysmex XE－5000혈세포분석의검측고형광세포수병도편염색경검，운용수시자공작특정（receiver operating characteristic，ROC）곡선，분석연구흉복수고형광세포사사악성적액적령민도、특이성、양성사연비급음성사연비，탐토고형광세포대악성적액적진단개치。결과：악성종류환자조고형광세포수명현고우비악성종류환자조（Z=－7.372，P<0.05），고형광세포수곡선하면적（area under curve，AUC）위0.801，령민도70.67%，특이성84.31%，양성사연비4.50，음성사연비0.35。결론：검측흉복수고형광세포가용우악성적액적사사，당흉복수표본고형광세포수림계치（cut－off치）≥68시，응진일보검사병근종수방。
To study the value of high-fluorescent cell for the screening of malignant hydrothorax or ascites. The clinical diagnosis results and hydrothorax or ascites specimens of 400 outpatients registered from January to December in 2014 were collected, and high-fluorescent cells were counted with Sysmex XE-5000 blood cell analyzer, and then stained for microscopy. Receiver operating characteristic (ROC) curve was used to explore the sensitivity, speci-ficity, positive likelihood ratio and negative likelihood ratio of high-fluorescent cell for screening malignant hydrothorax or ascites. The numbers of high-fluorescent cells of the cancer patients were significantly higher than those of the non-cancer patients, with Z equal to -7.372 and P less than 0.05. The values of the area under curve (AUC), sensitivity, specificity, positive likelihood ratio and negative likelihood ratio were 0.801, 70.67%, 84.31%, 4.50 and 0.35 respective-ly. Detection of high-fluorescent may be used to screen malignant hydrothorax or ascites, and further exami-nation and follow-up have to be performed in case the number of high-fluorescent cells in the hydrothorax or ascites is not less than 68.
