CAJ | 학술논문

目的：探讨T2DM患者胆囊排空功能的改变与胆囊动脉血流动力学的关系。方法超声测定胆囊体积、胆囊排空功能及胆囊动脉血流。结果 T2DM组较NC组空腹胆囊体积（FV ）及脂餐后胆囊体积（RV）增大，胆囊排空率（EF）减低（P＜0.01）；胆囊动脉阻力指数（RI）升高[（0.61±0.06） vs （0.70±0.08）]（P＜0.01），舒张期最低流速（Vmin）降低[（8.72±1.43） vs （6.05±1.89）cm／s]（P＜0.01）。相关分析结果显示，胆囊动脉RI与 HbA1 c、LDL‐C呈正相关（r＝0.827，0.820，P＜0.01）。结论 T2DM患者胆囊排空功能降低与胆囊动脉血流动力学改变相关。
목적：탐토T2DM환자담낭배공공능적개변여담낭동맥혈류동역학적관계。방법초성측정담낭체적、담낭배공공능급담낭동맥혈류。결과 T2DM조교NC조공복담낭체적（FV ）급지찬후담낭체적（RV）증대，담낭배공솔（EF）감저（P＜0.01）；담낭동맥조력지수（RI）승고[（0.61±0.06） vs （0.70±0.08）]（P＜0.01），서장기최저류속（Vmin）강저[（8.72±1.43） vs （6.05±1.89）cm／s]（P＜0.01）。상관분석결과현시，담낭동맥RI여 HbA1 c、LDL‐C정정상관（r＝0.827，0.820，P＜0.01）。결론 T2DM환자담낭배공공능강저여담낭동맥혈류동역학개변상관。
Objective To explore the relationship of gallbladder emptying function and its hemodynamics in diabetic patients. Methods Gallbladder volume ,emptying function and its arterial blood flow were measured by ultrasound. Results The gallbladder volumes of fasting (FV ) and postprandial (RV) increased and the ejection fraction (EF) of gallbladder was decreased in DM group than in NC group (P<0.01). In DM group ,the gallbladder artery’s resistance index (RI) was higher than in NC group [(0.61 ± 0.06) vs (0.70 ± 0.08)](P<0.01). Minimum diastolic blood flow velocity (Vmin) was lower than in NC group [(8.72 ± 1.43) vs (6.05 ± 1.89)cm/s](P<0.01). RI was associated with HbA1c (r= 0.827 ,P< 0.01) and LDL‐C(r= 0.820 ,P< 0.01). Conclusion Gallbladder emptying dysfunction in diabetic patients is associated with the hemodynamics of gallbladder.